Protein Overview: TIR2

General Information:
Name(s) found:	TIR2 / YOR010C [SGD]
Description(s) found: Found 27 descriptions. SHOW ALL	Putative cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis [SGD]
Organism:	Saccharomyces cerevisiae
Length:	251 amino acids
Gene Ontology:
Cellular Component:	fungal-type cell wall [ISS]
Biological Process:	response to stress [IDA]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYIKIALLA AIAALASAQT QEEIDELNVI LNDVKSNLQE YISLAEDSSS GFSLSSLPSG  60
   61 VLDIGLALAS ATDDSYTTLY SEVDFAAVSK MLTMVPWYSS RLLPELESLL GTSTTAASST 120
  121 EASSAATSSA VASSSETTSS AVASSSEATS SAVASSSEAS SSAATSSAVA SSSEATSSTV 180
  181 ASSTKAASST KASSSAVSSA VASSTKASAI SQISDGQVQA TSTVSEQTEN GAAKAVIGMG 240
  241 AGVMAAAAML L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RPT3	TIR2	1	Unpublished Fields Lab Data
View Screen	RAD6	TIR2	1	Unpublished Fields Lab Data
View Screen	ATG7	TIR2	1	Unpublished Fields Lab Data
View Screen	YJR141W	TIR2	1	Unpublished Fields Lab Data
View Screen	UBC7	TIR2	1	Unpublished Fields Lab Data
View Screen	CTF13	TIR2	1	Unpublished Fields Lab Data
View Screen	NAF1	TIR2	1	Hazbun TR, et al. (2003)

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..119]	Pfam	57.958607	Seripauperin and TIP1 family Confident ab initio structure predictions are available.
2	View Details	[120..251]	MSA	1.056994	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2