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Protein Overview: YOL157C

General Information:
Name(s) found: YOL157C [SGD]
Description(s) found:
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  • gi|74627241|sp|Q08295.1|MALX4_YEAST RecName: Full=Probable alpha-glucosidase YOL157C; AltName: Full=Maltase [NCBI NR]
  • gi|6324416|ref|NP_014485.1| Putative protein of unknown function; Yol157cp [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S66856 probable membrane protein YOL157c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1420068|emb|CAA99179.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Probable alpha-glucosidase YOL157C OS=Saccharomyces cerevisiae GN=YOL157C PE=2 SV=1 [Swiss-Prot]
  • Strong similarity to alpha-glucosidases Mal12p, Mal32p, an mal62p [mips]
  • Putative protein of unknown function [SGD]
  • >Q08295 (Q08295) Chromosome XV reading frame ORF YOL157C [4932.FASTACCERV.txt]
  • Chr XV from 24293-22524, reverse complement [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XV from 22524-24293, reverse complement [yeastorf3.fasta]
  • YOL157C, Chr XV from 22524-24293, reverse complement [yeast_orfs2]
  • YOL157C SGDID:S0005517, Chr XV from 24293-22524, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • Yol157cp [Saccharomyces cerevisiae]gi|1420068|emb|CAA99179.1| unnamed protein product [Saccharomyces cerevisiae]gi|2118038|pir||S66856 probable membrane protein YOL157c - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas]
  • (Q08295) S.cerevisiae chromosome XV reading frame ORF YOL157c [cerv4932.FASTAC]
  • YOL157C SGDID:S000005517, Chr XV from 24293-22524, reverse complement, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YOL157C SGDID:S000005517, Chr XV from 24293-22524, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" [yeast-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Probable alpha-glucosidase YOL157C (Maltase) [nr-271106-contam.fasta]
  • Putative protein of unknown function; Yol157cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • IMA2 SGDID:S000005517, Chr XV from 24294-22525, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha-glucosidase with specificity for isomaltase, methyl-alpha-glucoside, and palatinose; member of IMA isomaltase family; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose" [yeast-030211-contam.fasta]
  • IMA2 SGDID:S000005517, Chr XV from 24294-22525, Genome Release 64-2-1, reverse complement, Verified ORF, "Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); preferred specificity for isomaltose, alpha-methylglucoside, and palatinose, but also exhibits alpha-1,2 glucosidase activity on sucrose and kojibiose, and can cleave the 1,3-alpha linkage of nigerose and turanose and the alpha-1,5 linkage of leucrose in vitro; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose" [20141208_orf_trans.fasta]
  • YOL157C SGDID:S000005517, Chr XV from 24294-22525, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha-glucosidase with specificity for isomaltase, methyl-alpha-glucoside, and palatinose; member of IMA isomaltase family; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 589 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTISSAHPET EPKWWKEATI YQIYPASFKD SNNDGWGDMK GIASKLEYIK ELGADAIWIS  60
   61 PFYDSPQDDM GYDIANYEKV WPTYGTNEDC FALIEKTHKL GMKFITDLVI NHCSSEHEWF 120
  121 KESRSSKTNP KRDWFFWRPP KGYDAEGKPI PPNNWRSYFG GSAWTFDEKT QEFYLRLFCS 180
  181 TQPDLNWENE DCRKAIYESA VGYWLDHGVD GFRIDVGSLY SKVAGLPDAP VIDENSKWQP 240
  241 SDPFTMNGPR IHEFHQEMNK FIRNRVKDGR EIMTVGEMQH ATDETKRLYT SASRHELSEL 300
  301 FNFSHTDVGT SPKFRQNLIP YELKDWKVAL AELFRYVNGT DCWSTIYLEN HDQPRSITRF 360
  361 GDDSPKNRVI SGKLLSVLLV SLSGTLYVYQ GQELGEINFK NWPIEKYEDV EVRNNYDAIK 420
  421 EEHGENSKEM KRFLEAIALI SRDHARTPMQ WSREEPNAGF SGPNAKPWFY LNESFREGIN 480
  481 AEDESKDPNS VLNFWKEALR FRKAHKDITV YGYDFEFIDL DNKKLFSFTK KYDNKTLFAA 540
  541 LNFSSDSIDF TIPNNSSSFK LEFGNYPRSE VDASSRTLKP WEGRIYISE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..302] PSI-BLAST 2170.0 Oligo-1,6-glucosidase; Oligo-1,6, glucosidase
    2 View Details [303..589] PSI-BLAST 2170.0 Oligo-1,6-glucosidase; Oligo-1,6, glucosidase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  5.72449317118946 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  5.38610972475995 bayes_pls_golite062009
  • hydrolase activity
    		•  4.42755848458375 bayes_pls_golite062009
  • hexosaminidase activity
    		•  2.6383220379017 bayes_pls_golite062009
  • chitinase activity
    		•  2.45357334610104 bayes_pls_golite062009
  • structural molecule activity
    		•  2.28030619331997 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  2.12259271877403 bayes_pls_golite062009
  • trehalase activity
    		•  2.11042620996316 bayes_pls_golite062009
  • alpha-amylase activity
    		•  2.09193270404736 bayes_pls_golite062009
  • amylase activity
    		•  2.03484942782894 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • glucosidase activity
    		•  1.63850753281742 bayes_pls_golite062009
  • transporter activity
    		•  1.28975867300692 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  1.09355005521552 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  1.08320932161637 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.06875155491269 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.798668027833638 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  0.726290283967376 bayes_pls_golite062009
  • galactosidase activity
    		•  0.67508380605029 bayes_pls_golite062009
  • binding
    		•  0.63693798355947 bayes_pls_golite062009
  • alpha-glucosidase activity
    		•  0.54694531123812 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.543615761700598 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.4998423581103 bayes_pls_golite062009
  • maltase activity
    		•  0.442635030512661 bayes_pls_golite062009
  • sugar binding
    		•  0.36459095255871 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.247544462005515 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle