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Protein Overview: HPF1

General Information:
Name(s) found: HPF1 / YOL155C [SGD]
Description(s) found:
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  • gi|6324418|ref|NP_014487.1| Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines; Hpf1p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S66852 hypothetical protein YOL155c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1420064|emb|CAA99177.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|119370761|sp|Q05164.2|HPF1_YEAST RecName: Full=Haze protective factor 1; Flags: Precursor [NCBI NR]
  • Haze protective factor 1 OS=Saccharomyces cerevisiae GN=HPF1 PE=1 SV=2 [Swiss-Prot]
  • Similarity to glucan 1,4-alpha-glucosidase Sta1p and YAR066w [mips]
  • Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines [SGD]
  • >Q08294 (Q08294) Chromosome XV reading frame ORF YOL155C [4932.FASTACCERV.txt]
  • Chr XV from 31605-28702, reverse complement [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XV from 28702-31605, reverse complement [yeastorf3.fasta]
  • YOL155C, Chr XV from 28702-31605, reverse complement [yeast_orfs2]
  • YOL155C SGDID:S0005515, Chr XV from 31605-28702, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • ORF [Saccharomyces cerevisiae]gi|1420064|emb|CAA99177.1| unnamed protein product [Saccharomyces cerevisiae]gi|2132025|pir||S66852 hypothetical protein YOL155c - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas]
  • (Q08294) S.cerevisiae chromosome XV reading frame ORF YOL155c [cerv4932.FASTAC]
  • YOL155C SGDID:S000005515, Chr XV from 31605-28702, reverse complement, Uncharacterized ORF, "ORF" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • HPF1 SGDID:S000005515, Chr XV from 31605-28702, reverse complement, Verified ORF, "Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines" [yeast-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines; Hpf1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Haze protective factor 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HPF1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • HPF1 SGDID:S000005515, Chr XV from 31606-28703, Genome Release 64-1-1, reverse complement, Verified ORF, "Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines" [yeast-030211-contam.fasta]
  • HPF1 SGDID:S000005515, Chr XV from 31606-28703, Genome Release 64-2-1, reverse complement, Verified ORF, "Haze-protective mannoprotein; reduces the particle size of aggregated proteins in white wines" [20141208_orf_trans.fasta]
  • YOL155C SGDID:S000005515, Chr XV from 31606-28703, Genome Release 64-1-1, reverse complement, Verified ORF, "Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 967 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed article]
    extracellular region [IDALink to PubMed article]
    Biological Process: cellular cell wall organization [IGILink to PubMed article]
    Molecular Function: glucosidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNRFNKLQA ALALVLYSQS ALGQYYTNSS SIASNSSTAV SSTSSGSVSI SSSIELTSST  60
   61 SDVSSSLTEL TSSSTEVSSS IAPSTSSSEV SSSITSSGSS VSGSSSITSS GSSVSSSSSA 120
  121 TESGSSASGS SSATESGSSV SGSSTSITSG SSSATESGSS VSGSTSATES GSSASGSSSA 180
  181 TESGSSASGS SSATESGSSV SGSSSATESG SSVSGSSSAT ESGSASSVPS SSGSVTESGS 240
  241 SSSASESSIT QSGTASGSSA SSTSGSVTQS GSSVSGSSAS SAPGISSSIP QSTSSASTAS 300
  301 GSITSGTLSS ITSSASSATA TASNSLSSSD GTIYLPSTTI SGDITLTGSV IATEAVEVAA 360
  361 GGKLTLLDGD KYVFSADFII HGGVFVEKSK PTYPGTEFDI SGENFDVSGT FNAEEPAASS 420
  421 ASAYSFTPGS FDNSGDISLS LSESTKGEVT FSPYSNSGAF SFSNAILNGG SVSGLQRRAE 480
  481 SGSVNNGEIN LENGSTYVVV EPVSGSGTIN IISGNLYLHY PDTFTGQTVV FKGEGVLAVD 540
  541 PTETNTTPIP VVGYTGENQI AITADVTALS YDSATGVLTA TQGNSQFSFS IGTGFSSSGF 600
  601 NVSEGTFAGA YAYYLNYGGV VASSATPSST STTSGATNST SGSTSFGASV TGSTASTSFG 660
  661 ASVTGSTAST LISGSPSVYT TTLTYATTTS TVVVSCSETT DSNGNVYTIT TTVPCSSTTA 720
  721 TITSCDETGC HVTTSTGTVA TETVSSKSYT TVTVTHCDNN GCNTKTVTSE CPEETSATTT 780
  781 SPKSYTTVTV THCDDNGCNT KTVTSEAPEA TTTTVSPKTY TTATVTQCDD NGCSTKTVTS 840
  841 EAPKETSETS ETSAAPKTYT TATVTQCDDN GCNVKIITSQ IPEATSTVTA TSASPKSYTT 900
  901 VTSEGSKATS LTTAISKASS AISTYSKSAA PIKTSTGIIV QSEGIAAGLN ANTLNALVGI 960
  961 FVLAFFN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) DSE2 HPF1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run YNL313C No Comments Hazbun TR, et al. (2003)
    View Run PAN1 No Comments Toshima J, et al (2006)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..428] MSA 8.180997 View MSA. No confident structure predictions are available.
    2 View Details [429..491] deduced N/A No confident structure predictions are available.
    3 View Details [492..967] MSA 9.197997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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