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Protein Overview: MDY2

General Information:
Name(s) found: MDY2 / YOL111C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Protein required for efficient mating; involved in shmoo formation and nuclear migration in the pre-zygote; associates with ribosomes and interacts with Get4p; has a possible role in insertion of tail-anchored proteins into the ER membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 212 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed articleLink to PubMed article]
    ribosome [IDALink to PubMed article]
    Biological Process: cell morphogenesis involved in conjugation with cellular fusion [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSASGPEH EFVSKFLTLA TLTEPKLPKS YTKPLKDVTN LGVPLPTLKY KYKQNRAKKL  60
   61 KLHQDQQGQD NAAVHLTLKK IQAPKFSIEH DFSPSDTILQ IKQHLISEEK ASHISEIKLL 120
  121 LKGKVLHDNL FLSDLKVTPA NSTITVMIKP NPTISKEPEA EKSTNSPAPA PPQELTVPWD 180
  181 DIEALLKNNF ENDQAAVRQV MERLQKGWSL AK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) GET4 MDY2 NIP100 SGT2 YBR137W YDR026C
    View Details Ho Y, et al. (2002) CIA1 DOG1 MDY2 MET18 RPN8 UBP9

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MDY2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..72] deduced N/A No confident structure predictions are available.
    2 View Details [73..212] PSI-BLAST 26.69897 Ubiquitin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.63877637096497 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.26268915216809 bayes_pls_golite062009
  • structural molecule activity
    		•  1.89635407400581 bayes_pls_golite062009
  • protein binding
    		•  1.89134588490127 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.729632027931987 bayes_pls_golite062009
  • tubulin binding
    		•  0.0390794819499503 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle