Protein Overview: IRC10

General Information:
Name(s) found:	IRC10 / YOL015W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74583681\|sp\|Q08118.1\|IRC10_YEAST RecName: Full=Uncharacterized protein IRC10; AltName: Full=Increased recombination centers protein 10 [NCBI NR] gi\|6324558\|ref\|NP_014627.1\| hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci; Irc10p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S66697 probable membrane protein YOL015w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1419789\|emb\|CAA99014.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Uncharacterized protein IRC10 OS=Saccharomyces cerevisiae GN=IRC10 PE=2 SV=1 [Swiss-Prot] Weak similarity to YKR015c [mips] Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci [SGD] >Q08118 (Q08118) Chromosome XV reading frame ORF YOL015W [4932.FASTACCERV.txt] Chr XV from 297078-298838 [hmr_yeast5_DM3-1_pombe.fasta] YOL015W, Chr XV from 297078-298838 [yeast_orfs2] YOL015W SGDID:S0005375, Chr XV from 297078-298838, Uncharacterized ORF [yeastflysequest.fasta] Yol015wp [Saccharomyces cerevisiae]gi\|1419789\|emb\|CAA99014.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|2132822\|pir\|\|S66697 probable membrane protein YOL015w - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas] (Q08118) S.cerevisiae chromosome XV reading frame ORF YOL015w [cerv4932.FASTAC] YOL015W SGDID:S000005375, Chr XV from 297078-298838, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YOL015W SGDID:S000005375, Chr XV from 297079-298839, Uncharacterized ORF, "Hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci" [yeast-contam.fasta] IRC10 SGDID:S000005375, Chr XV from 297079-298839, Verified ORF, "Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Uncharacterized protein IRC10 (Increased recombination centers protein 10) [nr-271106-contam.fasta] hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci; Irc10p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Uncharacterized protein IRC10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IRC10 PE=2 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] IRC10 SGDID:S000005375, Chr XV from 297078-298838, Genome Release 64-1-1, Verified ORF, "Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci" [yeast-030211-contam.fasta] IRC10 SGDID:S000005375, Chr XV from 297078-298838, Genome Release 64-2-1, Verified ORF, "Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci" [20141208_orf_trans.fasta] YOL015W SGDID:S000005375, Chr XV from 297078-298838, Genome Release 64-1-1, Verified ORF, "Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	586 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFIEYSRLPG FESINISFSR GMLRLAKFTN FATYKQKLEY FRLLAGSNKY IQRISVADFE  60
   61 RHPDEINYIY IILISILQME ECMPVLVLCP TVYWVRFHWP GKCSVNSLNF TNETLKSAFH 120
  121 AVFTPYFALM KKVLGRIKNN MLLFAEPHAN LNNLFVKHFH DLIYKSVKDE KTGEAILYLR 180
  181 TNVNVPNVFI DDKRAVFHGD GMKIGKFTGK FLCFSFKRTI RWSKLDSVDS FAVTTVNYRV 240
  241 SVNWEKTPRK TFLSLDSDTK NLHYISKKIL NKKGKNATTS KTTKSSCTSE NVCDDKTFSV 300
  301 EFPLTTSAKT EYLLRSNFSL EKINESNNPT LQELTLNRTH RLYRSNFRNE QSTTQRKFEK 360
  361 IGRTVSTDSG NKLLTFPEQK ATRDSNPFSI ELTHATVISS DESALKDTTN QAIAEMQRIT 420
  421 PAIAKTISRR TANWVCSNPA PDPYGEPSTW SRILTPNLKI ISESSPYYPV HLASPNSTFS 480
  481 RDQSVRSVVM RRSSVCVEKQ NSFFRNYEHF KNILSRRTIK VKTSCPRLSV DVSDNKRENL 540
  541 SQEHLILPNK SREKVNRFKN CLHRVAEALR AAKENWDQHN PRNSIH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#03 Alpha Factor Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RAD6	IRC10	1	Unpublished Fields Lab Data
View Screen	PRR1	IRC10	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..109]	MSA	2.003959	View MSA. No confident structure predictions are available.
2	View Details	[110..586]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2