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Protein Overview: PLB3

General Information:
Name(s) found: PLB3 / YOL011W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 686 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IDALink to PubMed article]
    plasma membrane [ISSLink to PubMed article]
    Biological Process: phosphoinositide metabolic process [IDALink to PubMed article][IMPLink to PubMed article]
    phosphatidylserine catabolic process [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: lysophospholipase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRPLCSKII ISYIFAISQF LLAANAWSPT DSYVPGTVSC PDDINLVREA TSISQNESAW  60
   61 LEKRNKVTSV ALKDFLTRAT ANFSDSSEVL SKLFNDGNSE NLPKIAVAVS GGGYRSMLTG 120
  121 AGVLAAMDNR TEGAYEHGLG GLLQSTTYLS GASGGNWLVG TLALNNWTSV QDILNNMQND 180
  181 DSIWDLSDSI VTPGGINIFK TAKRWDHISN AVESKQNADY NTSLADIWGR ALAYNFFPSL 240
  241 NRGGIGLTWS SIRDFPVFQN AEMPFPISVA DGRYPGTKVI NLNATVFEFN PFEMGSWDPS 300
  301 LNSFANVKYL GTNVSNGVPL ERGKCTAGFD NAGFIMGTSS TLFNQFLLRI NSTHLPSFIT 360
  361 RLARHFLKDL SQDFNDIAVY SPNPFKDTKF LDSDYTTSIV DSDSLFLVDG GEDDENVPVL 420
  421 PLIQKERDVD IIFAVDNSAD MRLAWPDGSS LVHTYERQFV KQGQGMSFPY VPDTNTFVNL 480
  481 GLNKKPTFFG CDANNLTDLQ YIPPLVVYLP NAEYSFNSNQ SAFKLSYSES QRRSMIQNGF 540
  541 EIATRNNFTD DPEFMGCVGC AIIRRKQQAL NITLPPECET CFKNYCWNGT LDTTPLPDVE 600
  601 KDVHHSFINV NSFNSSIGQE ESLYAGSSAS QSSSSSSSSS SSSEIPSATA TLEKKAATNS 660
  661 GSHLSGISVK FSAMIMLTLL MFTGAV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) PLB3 RPS10B SCM3 SUP35 SUP45 TRM12 VPS3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PLB3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..368] PSI-BLAST 136.156545 Domain from cytosolic phospholipase A2; Cytosolic phospholipase A2 catalytic domain
    2 View Details [369..613] ab initio 13.75 No description for 1cjyA was found.
    3 View Details [614..686] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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