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Protein Overview: AAD14

General Information:
Name(s) found: AAD14 / YNL331C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 376 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: cellular aldehyde metabolic process [ISSLink to PubMed article]
    Molecular Function: aryl-alcohol dehydrogenase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDLFKPLPE PPTELGRLRV LSKTAGIRVS PLILGGASIG DAWSGFMGSM NKEQAFELLD  60
   61 AFYEAGGNCI DTANSYQNEE SEIWIGEWMA SRKLRDQIVI ATKFTGDYKK YEVGGGKSAN 120
  121 YCGNHKRSLH VSVRDSLRKL QTDWIDILYI HWWDYMSSIE EVMDSLHILV QQGKVLYLGV 180
  181 SDTPAWVVSA ANYYATSHGK TPFSVYQGKW NVLNRDFERD IIPMARHFGM ALAPWDVMGG 240
  241 GRFQSKKAME ERKKNGEGLR TFVGGPEQTE LEVKISEALT KIAEEHGTES VTAIAIAYVR 300
  301 SKAKNVFPLI GGRKIEHLKQ NIEALSIKLT PEQIEYLESI VPFDVGFPKS LIGDDPAVTK 360
  361 KLSPLTSMSA RIAFDN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..242]
    [288..330]    		 PSI-BLAST 223.512579 Voltage-dependent K+ channel beta subunit
    2 View Details [243..287]
    [331..376]    		 PSI-BLAST 223.512579 Voltage-dependent K+ channel beta subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • aldo-keto reductase activity
    		•  2.57303336304449 bayes_pls_golite062009
  • aryl-alcohol dehydrogenase activity
    		•  2.5168190536972 bayes_pls_golite062009
  • catalytic activity
    		•  1.68179794468736 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.48881830724998 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47641884930911 bayes_pls_golite062009
  • binding
    		•  1.3044513338497 bayes_pls_golite062009
  • aldehyde reductase activity
    		•  1.16639404121425 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.11719422559274 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.04422492638189 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.977252981450468 bayes_pls_golite062009
  • potassium channel activity
    		•  0.728547795239835 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.630972936257947 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.523701620407407 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.502905594729202 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.459652878315688 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.458414323500097 bayes_pls_golite062009
  • 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity
    		•  0.207008954325429 bayes_pls_golite062009
  • trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
    		•  0.207008954325429 bayes_pls_golite062009
  • protein binding
    		•  0.013141318464947 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.53

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle