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Protein Overview: YNL234W

General Information:
Name(s) found: YNL234W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein of unknown function with similarity to globins; has a functional heme-binding domain; transcription is induced by hypoxia and other stress conditions; proposed to be involved in glucose signaling or metabolism; regulated by Rgt1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 426 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: response to stress [IEPLink to PubMed article]
    Molecular Function: heme binding [IPILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGEKILHSQ LLTNSDMSSG NVHHTKPMMY NVTLPSYNSS SIGPVDNLKI NERPGSHDHS  60
   61 MRSEMSSKNS GSDFMPQSIS RSEGSVYQVK IDRGDSPNTE GFDFKVNARD LLLLRMSWDI 120
  121 LLREYLTPKE LKVFQALLYS NKHITSTERP YLNTAPDGMI SKTIDPTARP RKTKQRDNDN 180
  181 KVDTALFCSQ FYDNLIAMDP LLEEYFPSLK HQAVSFCKVL DSAIDNLENV HVLDDYIVKL 240
  241 GKRHSRILGI KTVGFEVMGK AFMTTLQDRF GSFLTLELKN LWGQLYSYLA NCMITAGKDP 300
  301 MEKIQPDFSY NGDSVVLNFS IPKLAMHDIS TVNKLQMVKT KNATIPHNIT QVPTNKIPTE 360
  361 ILLDNSSTPI KSDRESTPPI SPKGSGSTKP SIGSSTVVES NTKKNNYDEK IHLLQKTAQQ 420
  421 KNCSIM

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CLU1 YJL144W YNL234W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CHK1 YNL234W 2 Unpublished Fields Lab Data
    View Screen YPT31 YNL234W 2 Unpublished Fields Lab Data
    View Screen CKB1 YNL234W 2 Unpublished Fields Lab Data
    View Screen YIF1 YNL234W 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YNL234W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] deduced N/A No confident structure predictions are available.
    2 View Details [156..365] PSI-BLAST 63.39794 Hemoglobin, alpha-chain
    3 View Details [366..426] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.855532651898837 bayes_pls_golite062009
  • protein binding
    		•  0.197317321564222 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle