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Protein Overview: ESBP6

General Information:
Name(s) found: ESBP6 / YNL125C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 673 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    membrane [ISSLink to PubMed article]
    Biological Process: transport [ISSLink to PubMed article]
    Molecular Function: transporter activity [ISSLink to PubMed article]
    [NOT]monocarboxylic acid transmembrane transporter activity [IGILink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTHSNDYFS ASSGMVSETS SEVSSINSSQ PVSFSKASIA APVPCSDLHS TKSNDASRKL  60
   61 SISRTLTNRL NDIKKAVDDD NLQTEENSAD VNKILESRFD VADAIRLQHN ESVQSKLNIP 120
  121 VTHTTTAGAS LSAPSSSAFS ASSIQNDTTE HKASMDSKLM RNRLYPASTK HSGKDLEAQG 180
  181 ITEFEPDEPT VKKVFTNKST GQLELPPDGG YGWVVTFCVF LTMFSTWGCN ASFGVDLAYY 240
  241 LNHDTYPGAS KYDYALIAGL TVFLGQLLSP LVMALMRIIG LRTTMLFGDA VMLAAYLLAS 300
  301 FTTKLWQLYV TQGFMVGCSI SLIFVPATTV LPGWFLKKRA VAMGVSLLGT GAGGVVYGLA 360
  361 TNKMLSDFGN TRWCLRIIGI SCSISVLVAI ALLKERNPTP AIGLKSPRAM FEQLKAMFSL 420
  421 KVITKPFVVL IALWFMFALF AYNMMVFTLS SYAISKGLSS HDASTLTAIL NGSQSIGRPL 480
  481 MGLAGDKFGR ANVTIVLTTL LTIYMFAFWI PAHTFVQLIF FSILVGSCVG VANVMNTVLI 540
  541 ADMVKPEEFL PAWAFVNYCG APFLLVCEVI AQALTVEKDK SNPYLHAQIF CGCCFIAALI 600
  601 LISILREYSI RMKLTERQAM TNEKLKEWKA SEYDTDSADE DWGKLKERKT KYDLLLGPGI 660
  661 KKYFLRMVYP MKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ESBP6 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..179] deduced N/A No confident structure predictions are available.
    2 View Details [180..673] PSI-BLAST 18.522879 No description for 1ja5A_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • binding
    		•  0.873217664940684 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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