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Protein Overview: TDA1

General Information:
Name(s) found: TDA1 / YMR291W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Putative kinase of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR291W is not an essential gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 586 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: protein kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTASSSASQ LQQRLPEEKP WPQLSGSNAD AQTFKCKYVT NHNSLGDGNF SVVKECMNIH  60
   61 TKDLYAMKLI KKQTVKNKIQ LIQREFDLLR SISEKIRDME KKNEHSLDIF EGHHHILQLF 120
  121 DYFETADNIV LITQLCQKGD LYEKIVENQC LDLETQVTSY CACLVSVLEF LHSQGIVHRD 180
  181 LKAENVLFRL RVNENEKNLQ GEHHGDFKYD LLAHDLVLAD FGLAAEYNTS KVNSLKEFVG 240
  241 TISYIAPEIV KCKGVGEMTP DQVGKLDKYG CPVDIWALGV LTYFMAFGYT PFDCTTDDET 300
  301 LECISKCDYY VDEQMMHDPK YEQFWNFVQC CFTIDPAVRR SAKNLKQHPF IKDYFATSNS 360
  361 LNTKDTPNFS FHPTIRRVSS TASMHTLRSP SKSRKTTTLA YLNMDGGSSE TSTAFSSKMD 420
  421 LPDLYVDRTI NSRERSLNRI RDTLKKTLSM TSLKPAGTFD YLHANKNGTS LSSSKSGLVK 480
  481 KNSTFVLDPK PPKNSLMNGC FSTTPESRSN FNTPKTLSRQ GSSTSVKKYV NEVDLLLTPR 540
  541 TASMSSNDTT AINDYDTTND KNPARKHAAS FQVNVDDSDG DETMQI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) DIN7 TDA1
    View Details Ho Y, et al. (2002) FUM1 TDA1 VPS33

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SNF4 TDA1 2 Uetz P, et al. (2000)

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TDA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138]
    [376..389]    		 PSI-BLAST 330.228787 Calmodulin-dependent protein kinase
    2 View Details [139..375] PSI-BLAST 330.228787 Calmodulin-dependent protein kinase
    3 View Details [390..484] PSI-BLAST 3.30103 No description for 1ew7C_ was found.
    4 View Details [485..586] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle