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View Structure Prediction Details

Protein: TDA1
Organism: Saccharomyces cerevisiae
Length: 586 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TDA1.

Description E-value Query
Range
Subject
Range
TDA1 - Putative kinase of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the...
gi|190408517 - gi|190408517|gb|EDV11782.1| hypothetical protein SCRG_02188 [Saccharomyces cerevisiae RM11-1a]
TDA1_YEAST - Serine/threonine-protein kinase TDA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TDA...
gi|207342044 - gi|207342044|gb|EDZ69925.1| YMR291Wp-like protein [Saccharomyces cerevisiae AWRI1631]
0.0 [1..586] [1..586]
gi|14029712 - gi|14029712|gb|AAK52801.1|AF363784_1 calcium-dependent protein kinase CDPK1 [Lycopersicon esculentum...
0.0 [3..469] [37..440]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..469] [45..450]
CDPKL_ARATH - Calcium-dependent protein kinase 21 OS=Arabidopsis thaliana GN=CPK21 PE=1 SV=1
0.0 [5..469] [46..446]
gi|4336426 - gi|4336426|gb|AAD17800.1| Ca2+-dependent protein kinase [Mesembryanthemum crystallinum]
0.0 [3..469] [48..452]
gi|13561063 - gi|13561063|emb|CAA65500.1| protein kinase [Medicago sativa]
0.0 [5..469] [54..454]
gi|5162880, gi|5... - gi|5162880|dbj|BAA81750.1| calcium-dependent protein kinase [Marchantia polymorpha], gi|5162877|dbj|...
0.0 [3..469] [41..448]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTASSSASQ LQQRLPEEKP WPQLSGSNAD AQTFKCKYVT NHNSLGDGNF SVVKECMNIH  60
   61 TKDLYAMKLI KKQTVKNKIQ LIQREFDLLR SISEKIRDME KKNEHSLDIF EGHHHILQLF 120
  121 DYFETADNIV LITQLCQK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [376-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRVSSTASMH TLRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 330.228787
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [139-375]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDLYEKIVEN QCLDLETQVT SYCACLVSVL EFLHSQGIVH RDLKAENVLF RLRVNENEKN  60
   61 LQGEHHGDFK YDLLAHDLVL ADFGLAAEYN TSKVNSLKEF VGTISYIAPE IVKCKGVGEM 120
  121 TPDQVGKLDK YGCPVDIWAL GVLTYFMAFG YTPFDCTTDD ETLECISKCD YYVDEQMMHD 180
  181 PKYEQFWNFV QCCFTIDPAV RRSAKNLKQH PFIKDYFATS NSLNTKDTPN FSFHPTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 330.228787
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [390-484]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSKSRKTTTL AYLNMDGGSS ETSTAFSSKM DLPDLYVDRT INSRERSLNR IRDTLKKTLS  60
   61 MTSLKPAGTF DYLHANKNGT SLSSSKSGLV KKNST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.30103
Match: 1ew7C_
Description: No description for 1ew7C_ was found.

Predicted Domain #4
Region A:
Residues: [485-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVLDPKPPKN SLMNGCFSTT PESRSNFNTP KTLSRQGSST SVKKYVNEVD LLLTPRTASM  60
   61 SSNDTTAIND YDTTNDKNPA RKHAASFQVN VDDSDGDETM QI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle