Protein Overview: ATR1

General Information:
Name(s) found:	ATR1 / YML116W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|798884\|emb\|CAA89102.1\| Atr1p [Saccharomyces cerevisiae] [NCBI NR] gi\|6323520\|ref\|NP_013591.1\| Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide; Atr1p [Saccharomyces cerevisiae] [NCBI NR] gi\|51830476\|gb\|AAU09767.1\| YML116W [Saccharomyces cerevisiae] [NCBI NR] gi\|1703757\|sp\|P13090.2\|ATR1_YEAST RecName: Full=Aminotriazole resistance protein [NCBI NR] pir\|\|S53956 aminotriazole resistance protein YML116w - yeast (Saccharomyces cerevisiae) [NCBI NR] Aminotriazole resistance protein OS=Saccharomyces cerevisiae GN=ATR1 PE=1 SV=2 [Swiss-Prot] ATR1 Putative substrate-H+ antiporter conferring resistance to aminotriazole [mips] Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide [SGD] ATR1, Chr XIII from 38196-39824 [yeast_orfs2] Chr XIII from 38196-39824 [yeastorf3.fasta] (P13090) Aminotriazole resistance protein [4932.FASTACCERV.txt] ATR1 SGDID:S0004584, Chr XIII from 38196-39824, Verified ORF [yeastflysequest.fasta] Atr1p [Saccharomyces cerevisiae]gi\|51830476\|gb\|AAU09767.1\| YML116W [Saccharomyces cerevisiae]gi\|798884\|emb\|CAA89102.1\| Atr1p [Saccharomyces cerevisiae]gi\|1703757\|sp\|P13090\|ATR1_YEAST Aminotriazole resistance proteingi\|1077029\|pir\|\|S53956 aminotriazole [nrdb_11152004_Chlamydomonas] ATR1 SGDID:S000004584, Chr XIII from 38196-39824, Verified ORF, "Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Aminotriazole resistance protein [nr-271106-contam.fasta] Atr1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YML116W [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide; Atr1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Aminotriazole resistance protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATR1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] ATR1 SGDID:S000004584, Chr XIII from 38196-39824, Genome Release 64-1-1, Verified ORF, "Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide" [yeast-030211-contam.fasta] ATR1 SGDID:S000004584, Chr XIII from 38196-39824, Genome Release 64-2-1, Verified ORF, "Multidrug efflux pump of the major facilitator superfamily; required for resistance to aminotriazole and 4-nitroquinoline-N-oxide; ATR1 has a paralog, YMR279C, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress" [20141208_orf_trans.fasta] YML116W SGDID:S000004584, Chr XIII from 38196-39824, Genome Release 64-1-1, Verified ORF, "Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	542 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [IMP][ISS]
Biological Process:	drug transmembrane transport [IMP]
Molecular Function:	boron transmembrane transporter activity [IMP] drug transmembrane transporter activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNQSLVVLT ESKGEYENET ELPVKKSSRD NNIGESLTAT AFTQSEDEMV DSNQKWQNPN  60
   61 YFKYAWQEYL FIFTCMISQL LNQAGTTQTL SIMNILSDSF GSEGNSKSWL MASFPLVSGS 120
  121 FILISGRLGD IYGLKKMLLV GYVLVIIWSL ICGITKYSGS DTFFIISRAF QGLGIAFVLP 180
  181 NVLGIIGNIY VGGTFRKNIV ISFVGAMAPI GATLGCLFAG LIGTEDPKQW PWAFYAYSIA 240
  241 AFINFVLSIY AIPSTIPTNI HHFSMDWIGS VLGVIGLILL NFVWNQAPIS GWNQAYIIVI 300
  301 LIISVIFLVV FIIYEIRFAK TPLLPRAVIK DRHMIQIMLA LFFGWGSFGI FTFYYFQFQL 360
  361 NIRQYTALWA GGTYFMFLIW GIIAALLVGF TIKNVSPSVF LFFSMVAFNV GSIMASVTPV 420
  421 HETYFRTQLG TMIILSFGMD LSFPASSIIF SDNLPMEYQG MAGSLVNTVV NYSMSLCLGM 480
  481 GATVETQVNS DGKHLLKGYR GAQYLGIGLA SLACMISGLY MVESFIKGRR ARAAAEYDCT 540
  541 VA

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		AQR1 ATR1 QDR2 QDR3

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	ATR1	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..490]	PSI-BLAST	6.39794	No description for 1lviA_ was found.
2	View Details	[491..542]	deduced	N/A	No confident structure predictions are available.

Protein Overview: ATR1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: