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Protein Overview: DAK1

General Information:
Name(s) found: DAK1 / YML070W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 584 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: glycerol catabolic process [ISSLink to PubMed article]
    response to stress [IMPLink to PubMed article]
    Molecular Function: glycerone kinase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAKSFEVTD PVNSSLKGFA LANPSITLVP EEKILFRKTD SDKIALISGG GSGHEPTHAG  60
   61 FIGKGMLSGA VVGEIFASPS TKQILNAIRL VNENASGVLL IVKNYTGDVL HFGLSAERAR 120
  121 ALGINCRVAV IGDDVAVGRE KGGMVGRRAL AGTVLVHKIV GAFAEEYSSK YGLDGTAKVA 180
  181 KIINDNLVTI GSSLDHCKVP GRKFESELNE KQMELGMGIH NEPGVKVLDP IPSTEDLISK 240
  241 YMLPKLLDPN DKDRAFVKFD EDDEVVLLVN NLGGVSNFVI SSITSKTTDF LKENYNITPV 300
  301 QTIAGTLMTS FNGNGFSITL LNATKATKAL QSDFEEIKSV LDLLNAFTNA PGWPIADFEK 360
  361 TSAPSVNDDL LHNEVTAKAV GTYDFDKFAE WMKSGAEQVI KSEPHITELD NQVGDGDCGY 420
  421 TLVAGVKGIT ENLDKLSKDS LSQAVAQISD FIEGSMGGTS GGLYSILLSG FSHGLIQVCK 480
  481 SKDEPVTKEI VAKSLGIALD TLYKYTKARK GSSTMIDALE PFVKEFTASK DFNKAVKAAE 540
  541 EGAKSTATFE AKFGRASYVG DSSQVEDPGA VGLCEFLKGV QSAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen RAD6 DAK1 1 Unpublished Fields Lab Data
    View Screen SPT23 DAK1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data DAK1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..352] ORFEUS 9.94 Monomeric isocitrate dehydrogenase
    2 View Details [353..584] ORFEUS 9.94 Monomeric isocitrate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glycerone kinase activity
    		•  3.66907507772019 bayes_pls_golite062009
  • binding
    		•  0.69038000262198 bayes_pls_golite062009
  • catalytic activity
    		•  0.142389024724964 bayes_pls_golite062009
  • protein binding
    		•  0.133716715271428 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle