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Protein Overview: CTS1

General Information:
Name(s) found: CTS1 / YLR286C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Endochitinase, required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 562 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    fungal-type cell wall [TASLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    extracellular region [IDALink to PubMed article]
    Biological Process: cytokinesis, completion of separation [IMPLink to PubMed article]
    chitin catabolic process [ICLink to PubMed article]
    Molecular Function: endochitinase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLLYIILLF TQFLLLPTDA FDRSANTNIA VYWGQNSAGT QESLATYCES SDADIFLLSF  60
   61 LNQFPTLGLN FANACSDTFS DGLLHCTQIA EDIETCQSLG KKVLLSLGGA SGSYLFSDDS 120
  121 QAETFAQTLW DTFGEGTGAS ERPFDSAVVD GFDFDIENNN EVGYSALATK LRTLFAEGTK 180
  181 QYYLSAAPQC PYPDASVGDL LENADIDFAF IQFYNNYCSV SGQFNWDTWL TYAQTVSPNK 240
  241 NIKLFLGLPG SASAAGSGYI SDTSLLESTI ADIASSSSFG GIALWDASQA FSNELNGEPY 300
  301 VEILKNLLTS ASQTATTTVA TSKTSAASTS SASTSSASTS QKKTTQSTTS TQSKSKVTLS 360
  361 PTASSAIKTS ITQTTKTLTS STKTKSSLGT TTTESTLNSV AITSMKTTLS SQITSAALVT 420
  421 PQTTTTSIVS SAPIQTAITS TLSPATKSSS VVSLQTATTS TLSPTTTSTS SGSTSSGSTS 480
  481 SDSTARTLAK ELNAQYAAGK LNGKSTCTEG EIACSADGKF AVCDHSAWVY MECASGTTCY 540
  541 AYDSGDSVYT QCNFSYLESN YF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CTS1 DSE4 PGU1 SUC2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)
    View Run MLP2 #06 Alpha Factor Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data CTS1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..303] PSI-BLAST 459.40824 Hevamine A (chitinase/lysozyme)
    2 View Details [304..562] ORFEUS 14.75 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • chitinase activity
    		•  5.52705867024 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  5.36248919165223 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.55801959095491 bayes_pls_golite062009
  • glucosidase activity
    		•  3.69195576225095 bayes_pls_golite062009
  • hydrolase activity
    		•  3.15917910181967 bayes_pls_golite062009
  • beta-glucosidase activity
    		•  3.14931331494576 bayes_pls_golite062009
  • endochitinase activity
    		•  2.28901334624914 bayes_pls_golite062009
  • glucan 1,3-beta-glucosidase activity
    		•  1.95556875132062 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • alpha-amylase activity
    		•  1.42264105957213 bayes_pls_golite062009
  • amylase activity
    		•  1.37652764526134 bayes_pls_golite062009
  • chitin binding
    		•  1.29046765706168 bayes_pls_golite062009
  • binding
    		•  0.805431408845151 bayes_pls_golite062009
  • hexosaminidase activity
    		•  0.763360027922833 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.4998423581103 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  0.263065978664289 bayes_pls_golite062009
  • alpha-glucosidase activity
    		•  0.233746264236759 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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