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View Structure Prediction Details

Protein: CTS1
Organism: Saccharomyces cerevisiae
Length: 562 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CTS1.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-82 [1..562] [1..562]
CTS1 - Endochitinase, required for cell separation after mitosis; transcriptional activation during the G1 ...
CHIT_YEAST - Endochitinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CTS1 PE=1 SV=2
1.0E-82 [1..562] [1..562]
CHIA_TOBAC - Acidic endochitinase OS=Nicotiana tabacum PE=1 SV=1
7.0E-74 [1..303] [1..291]
CHIA_PHAAN - Acidic endochitinase OS=Phaseolus angularis PE=2 SV=1
1.0E-71 [1..303] [5..298]
gi|2342461 - gi|2342461|dbj|BAA21874.1| acidic endochitinase [Arabidopsis thaliana]
8.0E-71 [1..303] [4..302]
gi|2342465 - gi|2342465|dbj|BAA21876.1| acidic endochitinase [Arabis glabra]
1.0E-70 [4..303] [11..302]

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Predicted Domain #1
Region A:
Residues: [1-303]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLLYIILLF TQFLLLPTDA FDRSANTNIA VYWGQNSAGT QESLATYCES SDADIFLLSF  60
   61 LNQFPTLGLN FANACSDTFS DGLLHCTQIA EDIETCQSLG KKVLLSLGGA SGSYLFSDDS 120
  121 QAETFAQTLW DTFGEGTGAS ERPFDSAVVD GFDFDIENNN EVGYSALATK LRTLFAEGTK 180
  181 QYYLSAAPQC PYPDASVGDL LENADIDFAF IQFYNNYCSV SGQFNWDTWL TYAQTVSPNK 240
  241 NIKLFLGLPG SASAAGSGYI SDTSLLESTI ADIASSSSFG GIALWDASQA FSNELNGEPY 300
  301 VEI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 459.40824
Match: 1hvq__
Description: Hevamine A (chitinase/lysozyme)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
chitinase activity 5.52705867024 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 5.36248919165223 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.55801959095491 bayes_pls_golite062009
glucosidase activity 3.69195576225095 bayes_pls_golite062009
hydrolase activity 3.15917910181967 bayes_pls_golite062009
beta-glucosidase activity 3.14931331494576 bayes_pls_golite062009
endochitinase activity 2.28901334624914 bayes_pls_golite062009
glucan 1,3-beta-glucosidase activity 1.95556875132062 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
alpha-amylase activity 1.42264105957213 bayes_pls_golite062009
amylase activity 1.37652764526134 bayes_pls_golite062009
chitin binding 1.29046765706168 bayes_pls_golite062009
binding 0.805431408845151 bayes_pls_golite062009
hexosaminidase activity 0.763360027922833 bayes_pls_golite062009
carbohydrate binding 0.4998423581103 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.266938437560648 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 0.263065978664289 bayes_pls_golite062009
alpha-glucosidase activity 0.233746264236759 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [304-562]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKNLLTSASQ TATTTVATSK TSAASTSSAS TSSASTSQKK TTQSTTSTQS KSKVTLSPTA  60
   61 SSAIKTSITQ TTKTLTSSTK TKSSLGTTTT ESTLNSVAIT SMKTTLSSQI TSAALVTPQT 120
  121 TTTSIVSSAP IQTAITSTLS PATKSSSVVS LQTATTSTLS PTTTSTSSGS TSSGSTSSDS 180
  181 TARTLAKELN AQYAAGKLNG KSTCTEGEIA CSADGKFAVC DHSAWVYMEC ASGTTCYAYD 240
  241 SGDSVYTQCN FSYLESNYF

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.75
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle