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Protein Overview: ARV1

General Information:
Name(s) found: ARV1 / YLR242C [SGD]
Description(s) found:
Found 32 descriptions.
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  • Protein functioning in transport of glycosylphosphatidylinositol intermediates into the ER lumen; required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 321 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISSLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: sterol transport [IMPLink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    sterol metabolic process [ISSLink to PubMed article]
    sphingolipid metabolic process [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MICITCMRPV DSLYTVYSND HIQLTDCPYC QETVDKYVEI DNVLLFIDLL LLKAGAYRHL  60
   61 VFNALELHLS KYPKRKALND CQCLRDYTQA LLFNVKNWFC KYDRLNRLWL LLLSFEIYLT 120
  121 WVTEESKYIY YLNRNNNDGK LIMLSKKLPE SFKWDSAIMR NTITSKVFTW SPPIQYLYFA 180
  181 SYCILDVSLF HTFTQYFILK KLHWKHYSVS SKDVISYTIL LSYGAKIFPI LMLIWPYDTL 240
  241 ISMSIIKWVA NLYIIESLKI VTNLSYWNII KIFISVSLLR YFMVKPILIV FVAKFNFSVI 300
  301 KNLIHQEFIL LLQKSGTYLL L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] MSA 5.009983 View MSA. Confident ab initio structure predictions are available.
    2 View Details [136..321] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [162..321] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.84624717401156 bayes_pls_golite062009
  • protein binding
    		•  1.70162902007087 bayes_pls_golite062009
  • transporter activity
    		•  1.30067041733468 bayes_pls_golite062009
  • receptor activity
    		•  1.27081218639227 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.1514442454341 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.15037818154029 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07971596062462 bayes_pls_golite062009
  • DNA binding
    		•  1.07906220177233 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.809838091223165 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.555014154605011 bayes_pls_golite062009
  • transcription factor activity
    		•  0.4825638884734 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.253562998805943 bayes_pls_golite062009
  • signal transducer activity
    		•  0.212488443103452 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.212488443103452 bayes_pls_golite062009
  • catalytic activity
    		•  0.133319360419662 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.0849070471490733 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle