Protein Overview: REX3

General Information:
Name(s) found:	REX3 / YLR107W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74676521\|sp\|Q12090.1\|REXO3_YEAST RecName: Full=RNA exonuclease 3 [NCBI NR] gi\|6323136\|ref\|NP_013208.1\| RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases; Rex3p [Saccharomyces c [NCBI NR] pir\|\|S64944 hypothetical protein YLR107w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1360496\|emb\|CAA97672.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|1297021\|emb\|CAA61685.1\| L2904 [Saccharomyces cerevisiae] [NCBI NR] gi\|1256855\|gb\|AAB67549.1\| Ylr107wp [Saccharomyces cerevisiae] [NCBI NR] RNA exonuclease 3 OS=Saccharomyces cerevisiae GN=REX3 PE=1 SV=1 [Swiss-Prot] REX3 RNA exonuclease, member of the family of 3` -5` exonucleases [mips] RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases [SGD] REX3, Chr XII from 364117-365331 [yeast_orfs2] Chr XII from 364117-365331 [yeastorf3.fasta] >Q12090 (Q12090) Similar to S. POMBE hypothetical protein C22G7.04P (YLR107WP) [4932.FASTACCERV.txt] REX3 SGDID:S0004097, Chr XII from 364117-365331, Verified ORF [yeastflysequest.fasta] RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases [Saccharomyces cerevisiae]gi\|1297021\|emb\|CAA61685. [nrdb_11152004_Chlamydomonas] (Q12090) Ylr107wp (ORF YLR107w) (L2904 protein) [cerv4932.FASTAC] REX3 SGDID:S000004097, Chr XII from 364117-365331, Verified ORF, "RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family o [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] L2904 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] RNA exonuclease 3 [nr-271106-contam.fasta] Ylr107wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases; Rex3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] REX3 SGDID:S000004097, Chr XII from 364117-365331, Verified ORF, "RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases" [yeast-bovrabprots.fasta] [chemostatdb.fasta] RNA exonuclease 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=REX3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] REX3 SGDID:S000004097, Chr XII from 364116-365330, Genome Release 64-1-1, Verified ORF, "RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases" [yeast-030211-contam.fasta] REX3 SGDID:S000004097, Chr XII from 364116-365330, Genome Release 64-2-1, Verified ORF, "RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases" [20141208_orf_trans.fasta] YLR107W SGDID:S000004097, Chr XII from 364116-365330, Genome Release 64-1-1, Verified ORF, "RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	404 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA]
Biological Process:	RNA processing [IMP]
Molecular Function:	3'-5' exonuclease activity [IMP][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSLLRPVDL VNQPLGFQER YKILQKLFKQ LQKAYAHTKG TNIDLERLAT RLEVHVAKNS  60
   61 LSGQSYKFNM SILLRDVLKY KGDLSKIKIN GRPLKGAKPH LSSIGNANSI TTKSKAMEAL 120
  121 KALILDSKVL EKNGYIVKEM QNKTNDDNST QLYAPCLRCS SNFKKTDIME KTLCRYHPLK 180
  181 RIYNRDTKNH QYPCCGETTD SVSFLRLGCK TFFHHVFRGE SYDELCKISK FSSTDDIDGV 240
  241 ENVLSLDCEM AFTSLGYEMI RLTIVDFFTG KTLFDHVIQP IGDIVDLNSD FSGVHEIDRT 300
  301 NCPTYKEALD VFLSENLINK NSILIGHGLE NDLNVMRLFH NKVIDTAILY SRTKFKVSLK 360
  361 NLAFEVLSRK IQNGEHDSSQ DAIATMDVVK VKIGISPSQN KWEK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	REX3	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..189]	deduced	N/A	No confident structure predictions are available.
2	View Details	[190..404]	PSI-BLAST	2.69897	Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: REX3

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: