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Protein Overview: REX3

General Information:
Name(s) found: REX3 / YLR107W [SGD]
Description(s) found:
Found 27 descriptions.
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  • RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 404 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: RNA processing [IMPLink to PubMed article]
    Molecular Function: 3'-5' exonuclease activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSLLRPVDL VNQPLGFQER YKILQKLFKQ LQKAYAHTKG TNIDLERLAT RLEVHVAKNS  60
   61 LSGQSYKFNM SILLRDVLKY KGDLSKIKIN GRPLKGAKPH LSSIGNANSI TTKSKAMEAL 120
  121 KALILDSKVL EKNGYIVKEM QNKTNDDNST QLYAPCLRCS SNFKKTDIME KTLCRYHPLK 180
  181 RIYNRDTKNH QYPCCGETTD SVSFLRLGCK TFFHHVFRGE SYDELCKISK FSSTDDIDGV 240
  241 ENVLSLDCEM AFTSLGYEMI RLTIVDFFTG KTLFDHVIQP IGDIVDLNSD FSGVHEIDRT 300
  301 NCPTYKEALD VFLSENLINK NSILIGHGLE NDLNVMRLFH NKVIDTAILY SRTKFKVSLK 360
  361 NLAFEVLSRK IQNGEHDSSQ DAIATMDVVK VKIGISPSQN KWEK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data REX3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] deduced N/A No confident structure predictions are available.
    2 View Details [190..404] PSI-BLAST 2.69897 Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle