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Protein Overview: ENT4

General Information:
Name(s) found: ENT4 / YLL038C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein of unknown function, contains an N-terminal epsin-like domain; proposed to be involved in the trafficking of Arn1p in the absence of ferrichrome [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 247 amino acids

    Gene Ontology:
    Cellular Component: actin cortical patch [IPILink to PubMed article]
    Biological Process: actin filament organization [ISSLink to PubMed article]
    endocytosis [ISSLink to PubMed article]
    actin cortical patch assembly [ISSLink to PubMed article]
    Molecular Function: clathrin binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLLDTFKSF IQSPTESKVK QATNEDETSG ATGTLMNEIS ILTYSPKTVR EIIQVIRKRL  60
   61 LLGQNRRNSH RNCIQVMKTL TLVSYLMNNG SNEFIKWLKG NMILIEILED FQVQDPRDER 120
  121 KAEDIQKLSR NVLGLLQDDG LLEKQRKDVI QFRSSISTPG RKSTDNSHLK LEEMRSELTR 180
  181 QSLEKKAKPP TTSTSLDFQR QRTRNTHEYA RFSLDPLAEE DSEDTPGVAG GISKLSFRPK 240
  241 SSNNPFR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ENT1 ENT2 ENT4 PAN1 SLA1 YAP1801

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen IML1 ENT4 2 Unpublished Fields Lab Data
    View Screen HBT1 ENT4 2 Unpublished Fields Lab Data
    View Screen SPO21 ENT4 2 Unpublished Fields Lab Data
    View Screen YDR413C ENT4 2 Unpublished Fields Lab Data
    View Screen SPO21 ENT4 2 Unpublished Fields Lab Data
    View Screen BEM4 ENT4 2 Unpublished Fields Lab Data
    View Screen IQG1 ENT4 2 Unpublished Fields Lab Data
    View Screen MLC1 ENT4 2 Unpublished Fields Lab Data
    View Screen TOS3 ENT4 2 Unpublished Fields Lab Data
    View Screen VAM7 ENT4 1 Unpublished Fields Lab Data
    View Screen AML1 ENT4 1 Unpublished Fields Lab Data
    View Screen PUT2 ENT4 1 Unpublished Fields Lab Data
    View Screen MSH1 ENT4 1 Unpublished Fields Lab Data
    View Screen RPP0 ENT4 1 Unpublished Fields Lab Data
    View Screen SST2 ENT4 1 Unpublished Fields Lab Data
    View Screen YIF1 ENT4 1 Unpublished Fields Lab Data
    View Screen SPO21 ENT4 1 Unpublished Fields Lab Data
    View Screen LSM4 ENT4 1 Unpublished Fields Lab Data
    View Screen BRR2 ENT4 1 Unpublished Fields Lab Data
    View Screen SGF73 ENT4 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ENT4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..162] PSI-BLAST 172.165202 Epsin 1
    2 View Details [163..247] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • clathrin binding
    		•  2.70535896247543 bayes_pls_golite062009
  • binding
    		•  2.34501465852339 bayes_pls_golite062009
  • protein binding
    		•  1.97365365208963 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate binding
    		•  1.20269437433936 bayes_pls_golite062009
  • phosphoinositide binding
    		•  0.87586037360588 bayes_pls_golite062009
  • phospholipid binding
    		•  0.84481265656013 bayes_pls_golite062009
  • lipid binding
    		•  0.176990783274449 bayes_pls_golite062009
  • GTPase binding
    		•  0.0887270623721197 bayes_pls_golite062009
  • small GTPase binding
    		•  0.0268749201897704 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle