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Protein Overview: LAS1

General Information:
Name(s) found: LAS1 / YKR063C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Essential nuclear protein possibly involved in bud formation and morphogenesis; mutants require the SSD1-v allele for viability [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 502 amino acids

    Gene Ontology:
    Cellular Component: nucleus [TASLink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: budding cell bud growth [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPPRIVPWR DFAELEELKL WFYPKSKGTI EDKRQRAVQR VQSYRLKGSQ YLPHVVDSTA  60
   61 QITCAVLLDE KEACLGVHQD SIPIRLSYVM ALIRFVNGLL DPTQQSQFAI PLHTLAAKIG 120
  121 LPSWFVDLRH WGTHERDLPG LEMLRWAANE ALSWLYDHYW NDEELEDDRD DDDDDDDTGY 180
  181 GYRRNDKLEK YMESLTKTLD KWKRLRNEFL EYKWVWENAN DSLITSSNFS GDNLVNYDAE 240
  241 KRKSSHASSS ETMIRENLRQ WQELWKLSIY HNVVLEKFFN NYDPLLLKVL MLNLNNFDWK 300
  301 VIEWVARNYR TQQDDSNITT ILKRKFNAWK ELQKRLLDVI INNLNNKNFK NKWQNWEKLI 360
  361 DENASYLILY FCQSMLAKLE TEKITGNSWR NKKRRKQIDS TVEIEAKLKE NIDNLSLRFN 420
  421 EGEIKLYDFI PAEKDSVPLK KEVSPALKAD TNDILGDLAS LKQRMSSFGT VGKKNKQEEN 480
  481 RATPVKNWSR VQNWKPKPFG VL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) LAS1 MRS6 SFP1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data LAS1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..23]
    [43..53]
    [177..361]    		 ORFEUS 7.18 (+)-bornyl diphosphate synthase
    2 View Details [24..42]
    [54..176]    		 ORFEUS 7.18 (+)-bornyl diphosphate synthase
    3 View Details [362..502] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle