Protein Overview: YSR3

General Information:
Name(s) found:	YSR3 / YKR053C [SGD]
Description(s) found: Found 24 descriptions. SHOW ALL	Dihydrosphingosine 1-phosphate phosphatase, membrane protein involved in sphingolipid metabolism; has similarity to Lcb3p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	404 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA ]
Biological Process:	sphingolipid biosynthetic process [TAS]
Molecular Function:	sphingosine-1-phosphate phosphatase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIIQTVTEL GVTEDTIKVQ MAPSGGKHLL ADPGNHPAEH FESQMSWLRF QTRQYLTRFT  60
   61 DNQSDFVHSL QKKHRTPFRD VYFKYTSLMG SHMFYVIVLP MPVWLGYRDL TRDMIYVLGY 120
  121 SIYLSGYLKD YWCLPRPKSP PVDRITLSEY TTKEYGAPSS HSANATAVSL LFFWRICLSD 180
  181 TLVWPTKLLL LSLVIFYYLT LVFGRVYCGM HGMLDLFSGA AVGAICFFIR IWVVHALRNF 240
  241 QIGEHLWFPL LSVAWGLFIL FNHVRPIDEC PCFEDSVAFI GVVSGLDCSD WLTERYGWNL 300
  301 VCSRYASCGS KVFLRPLVGV ASVIVWKDVI SKTAVYTLLI KLLRFHDDRS EKVHFHNETS 360
  361 EEEECLLYSG VSKVEIVGRF LIYAGIPTTV FLLCPVFFTW TNLR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#29 Asynchronous Prep5-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CCE1	YSR3	1	Unpublished Fields Lab Data
View Screen	EST1	YSR3	1	Unpublished Fields Lab Data
View Screen	RAD6	YSR3	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..89]	deduced	N/A	No confident structure predictions are available.
2	View Details	[90..266]	PSI-BLAST	16.39794	Bacterial acid phosphatase
3	View Details	[267..404]	deduced	N/A	Confident ab initio structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2