YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: IRS4

General Information:
Name(s) found: IRS4 / YKR019C [SGD]
Description(s) found:
Found 26 descriptions.
SHOW ALL
  • EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 615 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: chromatin silencing at rDNA [IMPLink to PubMed article]
    cellular cell wall organization [IGILink to PubMed article]
    inositol lipid-mediated signaling [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLSFGKQRY HGGTTVTLTE QGASDSLRAA QAIFQNHSNE VSSPCPPVTV SRNPQTRLSE  60
   61 PSLQKSGRKQ EQKKARIRTK QVPKIKTTAP NDVELSKKHR SSPAGKDNVS STAQMAAALA 120
  121 HSQSKLSSDN NSSHSSALDT LKVLETPNLN GLLGIHSRSS SRNGSNESLT PGQRTPDNRS 180
  181 QENLLTSFSS GRRLSSSSME PATNKDSNKA LPKRRPSPPL QSSLVGSGQL HENENLSSIS 240
  241 IDSRHSLNPD TSDVISNRSQ TSLSQTINQL SLCESEPSIA SSNTTTTTSN QGSGLPNLVP 300
  301 NYSSDMRKKK LVNKFKRKVF GSKPKHLSSQ YEMDASSEEL GQHEQQPSMR FKTTLRKTSV 360
  361 STNAENDHAS SLHEGNLRYK YNPSNDTYDV YDDTDSDSES DQNQDALTKP RKRDRIKRKI 420
  421 RNSANKTAHH RPIHRTRDRK FNEDKPWKSH TDITFVTDNE RKRYESMWVS NRHRHLNLLS 480
  481 WWPSITGDSG AINTLPEDGL ILGIIVRDIW KRSNLPNSLL AEIYTKVDTR KDGTLDRKSF 540
  541 IVGMWLVDQC LYGRKLPNVV EQCVWDSVDR YASTTVVPVS TLKAMAKQKR KQMKEEIKNI 600
  601 KKENRVVLVD HNSSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YPT31 IRS4 1 Unpublished Fields Lab Data
    View Screen TOS3 IRS4 1 Unpublished Fields Lab Data
    View Screen YJR141W IRS4 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..474] deduced N/A No confident structure predictions are available.
    2 View Details [475..615] PSI-BLAST 72.36704 Eps15
    3 View Details [446..615] PSI-BLAST 35.045757 No description for 2qptA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle