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Protein Overview: AUR1

General Information:
Name(s) found: AUR1 / YKL004W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 401 amino acids

    Gene Ontology:
    Cellular Component: Golgi apparatus [IDALink to PubMed article]
    Biological Process: sphingolipid metabolic process [IMPLink to PubMed article]
    Molecular Function: inositol phosphoceramide synthase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANPFSRWFL SERPPNCHVA DLETSLDPHQ TLLKVQKYKP ALSDWVHYIF LGSIMLFVFI  60
   61 TNPAPWIFKI LFYCFLGTLF IIPATSQFFF NALPILTWVA LYFTSSYFPD DRRPPITVKV 120
  121 LPAVETILYG DNLSDILATS TNSFLDILAW LPYGLFHFGA PFVVAAILFV FGPPTVLQGY 180
  181 AFAFGYMNLF GVIMQNVFPA APPWYKILYG LQSANYDMHG SPGGLARIDK LLGINMYTTA 240
  241 FSNSSVIFGA FPSLHSGCAT MEALFFCYCF PKLKPLFIAY VCWLWWSTMY LTHHYFVDLM 300
  301 AGSVLSYVIF QYTKYTHLPI VDTSLFCRWS YTSIEKYDIS KSDPLAADSN DIESVPLSNL 360
  361 ELDFDLNMTD EPSVSPSLFD GSTSVSRSSA TSITSLGVKR A

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ADO1 AUR1 RRT14
    View Details Qiu et al. (2008) AUR1 VRG4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data AUR1 and COP1 Huh WK, et al. (2003)
    View Data AUR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..220] deduced N/A No confident structure predictions are available.
    2 View Details [221..345] ORFEUS 7.88 Bacterial acid phosphatase
    3 View Details [346..401] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.732568437339568 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle