YRC Public Data Repository - Protein Structure Prediction

Protein:	AUR1
Organism:	Saccharomyces cerevisiae
Length:	401 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AUR1.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[1..401]	[1..401]
gi\|2992150 - gi\|2992150\|dbj\|BAA25320.1\| Aur1-C [Shuttle vector pAUR112] gi\|2992148 - gi\|2992148\|dbj\|BAA25319.1\| Aur1-C [Shuttle vector pAUR101] gi\|2992152 - gi\|2992152\|dbj\|BAA25321.1\| Aur1-C [Shuttle vector pAUR123]	0.0	[1..401]	[1..401]
AUR1 - Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid ... gi\|151941542 - gi\|151941542\|gb\|EDN59905.1\| aureobasidin resistance protein [Saccharomyces cerevisiae YJM789] gi\|190409819 - gi\|190409819\|gb\|EDV13084.1\| aureobasidin A resistance protein [Saccharomyces cerevisiae RM11-1a] AUR1_YEAST - Inositol phosphorylceramide synthase catalytic subunit AUR1 OS=Saccharomyces cerevisiae (strain ATCC... gi\|207343437 - gi\|207343437\|gb\|EDZ70896.1\| YKL004Wp-like protein [Saccharomyces cerevisiae AWRI1631]	0.0	[1..401]	[1..401]
gi\|50291829, gi\|... - gi\|50291829\|ref\|XP_448347.1\| IPC1_CANGA [Candida glabrata], gi\|49527659\|emb\|CAG61308.1\| IPC1_CANGA [... gi\|4741881, gi\|4... - gi\|49527659\|emb\|CAG61308.1\| unnamed protein product [Candida glabrata], gi\|4741881\|gb\|AAD28745.1\|AF1...	0.0	[7..394]	[5..397]
gi\|4741885 - gi\|4741885\|gb\|AAD28747.1\|AF126178_1 inositolphosphorylceramide synthase; IPC1p [Candida parapsilosis...	0.0	[5..361]	[21..375]
AUR1_CANAL - Aureobasidin A resistance protein homolog OS=Candida albicans GN=AUR1 PE=3 SV=1	0.0	[5..396]	[18..414]
gi\|7144496 - gi\|7144496\|gb\|AAD28748.2\|AF126179_1 inositolphosphorylceramide synthase; IPC1p [Candida tropicalis]	0.0	[5..345]	[17..357]
gi\|4741883 - gi\|4741883\|gb\|AAD28746.1\|AF126177_1 inositolphosphorylceramide synthase; IPC1p [Issatchenkia orienta...	0.0	[9..380]	[15..391]
gi\|4558826 - gi\|4558826\|gb\|AAD22749.1\|AF076691_1 aureobasidin-resistance protein; AurA [Aspergillus nidulans]	0.0	[11..338]	[46..373]
gi\|4558828 - gi\|4558828\|gb\|AAD22750.1\|AF076692_1 aureobasidin-resistance protein; Aur1 homolog; Aur1 [Aspergillus...	0.0	[11..338]	[46..373]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANPFSRWFL SERPPNCHVA DLETSLDPHQ TLLKVQKYKP ALSDWVHYIF LGSIMLFVFI  60
   61 TNPAPWIFKI LFYCFLGTLF IIPATSQFFF NALPILTWVA LYFTSSYFPD DRRPPITVKV 120
  121 LPAVETILYG DNLSDILATS TNSFLDILAW LPYGLFHFGA PFVVAAILFV FGPPTVLQGY 180
  181 AFAFGYMNLF GVIMQNVFPA APPWYKILYG LQSANYDMHG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [221-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPGGLARIDK LLGINMYTTA FSNSSVIFGA FPSLHSGCAT MEALFFCYCF PKLKPLFIAY  60
   61 VCWLWWSTMY LTHHYFVDLM AGSVLSYVIF QYTKYTHLPI VDTSLFCRWS YTSIEKYDIS 120
  121 KSDPL

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.88
Match:	1d2tA
Description:	Bacterial acid phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.732568437339568	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [346-401]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AADSNDIESV PLSNLELDFD LNMTDEPSVS PSLFDGSTSV SRSSATSITS LGVKRA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: