YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: TIM8

General Information:
Name(s) found: TIM8 / YJR135W-A [SGD]
Description(s) found:
Found 30 descriptions.
SHOW ALL
  • Mitochondrial intermembrane space protein, forms a complex with Tim13p that delivers a subset of hydrophobic proteins to the TIM22 complex for inner membrane insertion; homolog of human TIMM8A, implicated in Mohr-Tranebjaerg syndrome [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 87 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial intermembrane space protein transporter complex [IDALink to PubMed article]
    Biological Process: protein import into mitochondrial inner membrane [IGILink to PubMed article][IMPLink to PubMed article][IPILink to PubMed articleLink to PubMed article]
    Molecular Function: protein transporter activity [IMPLink to PubMed article][IPILink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSTSDLA SLDDTSKKEI ATFLEGENSK QKVQMSIHQF TNICFKKCVE SVNDSNLSSQ  60
   61 EEQCLSNCVN RFLDTNIRIV NGLQNTR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) MDJ2 TIM10 TIM12 TIM13 TIM8 TIM9

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] Pfam 17.958607 Tim10/DDP family zinc finger No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle