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Protein Overview: TIM13

General Information:
Name(s) found: TIM13 / YGR181W [SGD]
Description(s) found:
Found 36 descriptions.
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  • Mitochondrial intermembrane space protein, forms a complex with Tim8p that delivers a subset of hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 105 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [IDALink to PubMed articleLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    mitochondrial intermembrane space protein transporter complex [IDALink to PubMed article]
    Biological Process: protein import into mitochondrial inner membrane [IMPLink to PubMed article][IPILink to PubMed articleLink to PubMed article]
    Molecular Function: protein transporter activity [IMPLink to PubMed article][IPILink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLSSIFGGG APSQQKEAAT TAKTTPNPIA KELKNQIAQE LAVANATELV NKISENCFEK  60
   61 CLTSPYATRN DACIDQCLAK YMRSWNVISK AYISRIQNAS ASGEI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) TIM10 TIM12 TIM13 TIM8 TIM9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run SEC10 No Comments De Craene, J., et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] Pfam 25.387216 Tim10/DDP family zinc finger No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  3.96569591038426 bayes_pls_golite062009
  • transporter activity
    		•  3.42555440535265 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  3.05578860381335 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  2.52072322460318 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  2.52072322460318 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26454691978513 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.01475009173074 bayes_pls_golite062009
  • binding
    		•  1.95236231715199 bayes_pls_golite062009
  • protein binding
    		•  1.54231655177329 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.5410808613005 bayes_pls_golite062009
  • unfolded protein binding
    		•  0.0997632819038001 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle