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Protein Overview: TES1

General Information:
Name(s) found: TES1 / YJR019C [SGD]
Description(s) found:
Found 32 descriptions.
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  • Peroxisomal acyl-CoA thioesterase likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 349 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: fatty acid oxidation [IEPLink to PubMed article][IMPLink to PubMed article]
    Molecular Function: acyl-CoA thioesterase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASKMAMSN LEKILELVPL SPTSFVTKYL PAAPVGSKGT FGGTLVSQSL LASLHTVPLN  60
   61 FFPTSLHSYF IKGGDPRTKI TYHVQNLRNG RNFIHKQVSA YQHDKLIFTS MILFAVQRSK 120
  121 EHDSLQHWET IPGLQGKQPD PHRYEEATSL FQKEVLDPQK LSRYASLSDR FQDATSMSKY 180
  181 VDAFQYGVME YQFPKDMFYS ARHTDELDYF VKVRPPITTV EHAGDESSLH KHHPYRIPKS 240
  241 ITPENDARYN YVAFAYLSDS YLLLTIPYFH NLPLYCHSFS VSLDHTIYFH QLPHVNNWIY 300
  301 LKISNPRSHW DKHLVQGKYF DTQSGRIMAS VSQEGYVVYG SERDIRAKF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) DCI1 FOX2 TES1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..349] PSI-BLAST 195.29073 Thioesterase II (TesB)
    2 View Details [131..349] FFAS03 7.51 Thioesterase II (TesB)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acyl-CoA thioesterase activity
    		•  2.60197973503923 bayes_pls_golite062009
  • CoA hydrolase activity
    		•  2.3187640589669 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  1.14159464719086 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  1.14125301545576 bayes_pls_golite062009
  • catalytic activity
    		•  0.74605540351792 bayes_pls_golite062009
  • binding
    		•  0.358549779743531 bayes_pls_golite062009
  • hydrolase activity
    		•  0.093543122203219 bayes_pls_golite062009
    2
    Term Confidence Notes
  • acyl-CoA thioesterase activity
    		•  2.09910961810984 bayes_pls_golite062009
  • CoA hydrolase activity
    		•  1.78895388806948 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  1.07218515999697 bayes_pls_golite062009
  • catalytic activity
    		•  0.713153177522975 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  0.68445696143302 bayes_pls_golite062009
  • binding
    		•  0.425102971682545 bayes_pls_golite062009
  • hydrolase activity
    		•  0.0388706889258174 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle