Protein Overview: PRY1

General Information:
Name(s) found:	PRY1 / YJL079C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|929877\|emb\|CAA58491.1\| J1022 [Saccharomyces cerevisiae] [NCBI NR] gi\|895901\|emb\|CAA61315.1\| hypothetical protein [Saccharomyces cerevisiae] [NCBI NR] gi\|6322382\|ref\|NP_012456.1\| Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins; Pry1p [Saccharomyces cerevisiae] [NCBI NR] gi\|45270502\|gb\|AAS56632.1\| YJL079C [Saccharomyces cerevisiae] [NCBI NR] gi\|1352994\|sp\|P47032.1\|PRY1_YEAST RecName: Full=Protein PRY1; AltName: Full=Pathogen related in Sc 1; Flags: Precursor [NCBI NR] pir\|\|S56031 pathogenesis-related protein homolog YJL079c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1008240\|emb\|CAA89372.1\| PRY1 [Saccharomyces cerevisiae] [NCBI NR] Protein PRY1 OS=Saccharomyces cerevisiae GN=PRY1 PE=1 SV=1 [Swiss-Prot] PRY1 Protein of unknown function [mips] Protein of unknown function [SGD] PRY1, Chr X from 289571-290470, reverse complement [yeast_orfs2] Chr X from 289571-290470, reverse complement [yeastorf3.fasta] Chr X from 290470-289571, reverse complement [yeastorf5.fasta] (P47032) PRY1 protein precursor (Pathogen related in Sc 1) [4932.FASTACCERV.txt] PRY1 SGDID:S0003615, Chr X from 290690-289791, reverse complement, Verified ORF [yeastflysequest.fasta] Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins [Saccharomyces cerevisiae]gi\|895901\|emb\|CAA61315.1\| hypothetical protein [Saccharomyces cerevisiae]gi\|1008240\|emb\|CAA89372.1\| PRY1 [S [nrdb_11152004_Chlamydomonas] PRY1 SGDID:S000003615, Chr X from 290690-289791, reverse complement, Verified ORF, "Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] PRY1 SGDID:S000003615, Chr X from 290769-289870, reverse complement, Verified ORF, "Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins" [yeast-contam.fasta] PRY1 SGDID:S000003615, Chr X from 290768-289869, reverse complement, Verified ORF, "Protein of unknown function" [yeast-200209-contam.fasta] PRY1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] J1022 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] hypothetical protein [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins; Pry1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YJL079C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein PRY1 precursor (Pathogen related in Sc 1) [nr-271106-contam.fasta] [chemostatdb.fasta] Protein PRY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRY1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] PRY1 SGDID:S000003615, Chr X from 290774-289875, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function" [yeast-030211-contam.fasta] PRY1 SGDID:S000003615, Chr X from 290774-289875, Genome Release 64-2-1, reverse complement, Verified ORF, "Sterol binding protein involved in the export of acetylated sterols; secreted glycoprotein and member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); sterol export function is redundant with that of PRY2; may be involved in detoxification of hydrophobic compounds; PRY1 has a paralog, PRY2, that arose from the whole genome duplication" [20141208_orf_trans.fasta] YJL079C SGDID:S000003615, Chr X from 290774-289875, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	299 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [IDA] endoplasmic reticulum [IDA] fungal-type vacuole [IDA] extracellular region [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLSKLSILT SALATSALAA PAVVTVTEHA HEAAVVTVQG VVYVENGQTR TTYETLAPAS  60
   61 TATPTSTATA LVAPPVAPSS ASSNSDVVLS ALKNLASVWG KTTDSTTTLT SSESTSQSLA 120
  121 QATTTSTPAA ASTTSTPAAT TTTSQAAATS SASSSDSDLS DFASSVLAEH NKKRALHKDT 180
  181 PALSWSDTLA SYAQDYADNY DCSGTLTHSG GPYGENLALG YDGPAAVDAW YNEISNYDFS 240
  241 NPGFSSNTGH FTQVVWKSTT QVGCGIKTCG GAWGDYVICS YDPAGNYEGE YADNVEPLA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	NAF1	PRY1	1	Hazbun TR, et al. (2003)

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	PRY1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..159]	ORFEUS	9.76	No description for 1ldvA was found.
2	View Details	[160..299]	PSI-BLAST	208.29073	Pathogenesis-related protein 1 (PR1)

Functions predicted (by domain):

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
binding	1.21670366786992	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2