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Protein Overview: RPR2

General Information:
Name(s) found: RPR2 / YIR015W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Subunit of nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; not shared between RNase MRP and RNase P, in contrast to all other RNase P protein subunits [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 144 amino acids

    Gene Ontology:
    Cellular Component: nucleolar ribonuclease P complex [IDALink to PubMed article]
    Biological Process: tRNA processing [TASLink to PubMed article]
    Molecular Function: ribonuclease P activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKAHGGKM KPEIDENGTL LVPPPRTIAN QDHFHRLNYL YQISAYQTRA RQKARTDAHT  60
   61 PLARNYIKSM DLISKKTKTS LLPTIKRTIC KKCHRLLWTP KKLEITSDGA LSVMCGCGTV 120
  121 KRFNIGADPN YRTYSEREGN LLNS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) POP1 POP3 POP4 POP5 POP6 POP7 POP8 RPP1 RPR2
    View Details Krogan NJ, et al. (2006) POP1 POP3 POP4 POP5 POP6 POP7 RMP1 RPP1 RPR2 SNM1
    View Details Qiu et al. (2008) POP1 POP3 POP4 POP5 POP6 POP7 POP8 RPP1 RPR2 SNM1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RPR2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] PSI-BLAST 23.39794 Crystal structure of ribonuclease P protein Ph1601p from Pyrococcus horikoshii OT3


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle