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Protein Overview: DJP1

General Information:
Name(s) found: DJP1 / YIR004W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Cytosolic J-domain-containing protein, required for peroxisomal protein import and involved in peroxisome assembly, homologous to E. coli DnaJ [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 432 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: protein import into peroxisome matrix [IMPLink to PubMed article]
    Molecular Function: chaperone binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVDTEYYDL LGVSTTASSI EIKKAYRKKS IQEHPDKNPN DPTATERFQA ISEAYQVLGD  60
   61 DDLRAKYDKY GRKEAIPQGG FEDAAEQFSV IFGGDAFASY IGELMLLKNL QKTEELNAED 120
  121 EAEKEKENVE TMEESPADGK TNGTTNAVDA ALGNTNEKDD KNKARTTSGN LTVHDGNKKN 180
  181 EQVGAEAKKK KTKLEQFEEE QEVEKQKRVD QLSKTLIERL SILTESVYDD ACKDSFKKKF 240
  241 EEEANLLKME SFGLDILHTI GDVYYEKAEI FLASQNLFGM GGIFHSMKAK GGVFMDTLRT 300
  301 VSAAIDAQNT MKELEKMKEA STNNEPLFDK DGNEQIKPTT EELAQQEQLL MGKVLSAAWH 360
  361 GSKYEITSTL RGVCKKVLED DSVSKKTLIR RAEAMKLLGE VFKKTFRTKV EQEEAQIFEE 420
  421 LVAEATKKKR HT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run SEC10 No Comments De Craene, J., et al. (2006)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run None Entered #17 Mitotic Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data DJP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..117] PSI-BLAST 143.70927 DnaJ chaperone, N-terminal (J) domain
    2 View Details [118..197] PSI-BLAST 17.69897 Cysteine-rich domain of the chaperone protein DnaJ.
    3 View Details [198..325] PSI-BLAST 15.045757 Heat shock protein 40 Sis1
    4 View Details [326..432] MSA 1.150976 View MSA. Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • unfolded protein binding
    		•  3.04403163860617 bayes_pls_golite062009
  • binding
    		•  2.4835091517649 bayes_pls_golite062009
  • heat shock protein binding
    		•  2.17994194200939 bayes_pls_golite062009
  • protein binding
    		•  1.81676109739118 bayes_pls_golite062009
  • chaperone binding
    		•  1.61155546076854 bayes_pls_golite062009
  • Hsp70 protein binding
    		•  0.541755903922701 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.423488346839872 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.146399219759372 bayes_pls_golite062009
  • catalytic activity
    		•  0.106988907594358 bayes_pls_golite062009
  • DNA binding
    		•  0.10307408349439 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.58201259799527 bayes_pls_golite062009
  • unfolded protein binding
    		•  2.04158808514315 bayes_pls_golite062009
  • protein binding
    		•  1.7866515791227 bayes_pls_golite062009
  • protein disulfide isomerase activity
    		•  0.290861970307477 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  0.290861970307477 bayes_pls_golite062009
  • catalytic activity
    		•  0.276917867171685 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  0.0964866497718595 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle