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Protein Overview: SYG1

General Information:
Name(s) found: SYG1 / YIL047C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Plasma membrane protein of unknown function; truncation and overexpression suppresses lethality of G-alpha protein deficiency [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 902 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: signal transduction [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFADHLTES AIPEWRDKYI DYKVGKKKLR RYKEKLDAEE EQSSSYRSWM PSVSVYQTAF  60
   61 QQREPGKSRS DGDYRSGPAF KKDYSALQRE FVADFIEDWL ISFQLSKCNE FYLWLLKECD 120
  121 KKFEVLQSQL HYYSLQKNYE RDNLNRSSSN VDMSTSLYAA GLAGRSDSRV NSIDSDSRSV 180
  181 MYGSMPCTKE AKKPRLSLLA YCQKVLKDNR LLPSWPKRGF SLLQDLRQDA SSRGRETFAF 240
  241 GASFLETMTT TQARNLLSNA IIEYYLYLQL VKSFRDINVT GFRKMVKKFD KTCHTRELTT 300
  301 FMSYARTHYT LFKHADANVQ LVAQKMQQIT SSQPTPTSEL SSAQRDKEPI TWLETQITEW 360
  361 FTTALTNSPK DRKHNTHKLK KLTIQYSISE QMVHRNNRSI VQMLVVGLGI GVSMTLITYT 420
  421 LYLGISSEET SFTHKILFPL WGGWYMVLLI AFLFLVNCFI WHRTGINYRF IMLGEIQSKN 480
  481 GTQFFNNDFA TSKIPLKLYF LTFFIVPCAV CSMLSFALEK LTPLGFLYIG IVSFLFLCPS 540
  541 GLIPYWDKVV HTRKWLVVTL IRLMMSGFFP VEFGDFFLGD IICSLTYSIA DIAMFFCVYS 600
  601 HTPNNLCGSS HSRAMGVLSC LPSYWRFMQC LRRFADSGDW FPHLLNAAKY TLGIAYNATL 660
  661 CAYRLSDRSE QRRTPFIVCA TLNSILTSAW DLVMDWSFAH NTTSYNWLLR DDLYLAGKKN 720
  721 WENGSYSFSR KLVYYFAMIW DILIRFEWIV YAIAPQTIQQ SAVTSFILAL LEVLRRFVWI 780
  781 IFRVENEHVA NVHLFRVTGD APLPYPIAQV GDDSMDSSDL GSKAFSSLND IPITPSHDNN 840
  841 PHSFAEPMPA YRGTFRRRSS VFENISRSIP WAHATDFQRP TVNTVDDRSP ETDSESEVES 900
  901 IM

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) RGP1 RIC1 SYG1 YIP3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run VAM3 Sample: HX11 - both fusion and trans-SNARE complex formation take place. Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SYG1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..434] PSI-BLAST 20.045757 Heavy meromyosin subfragment
    2 View Details [435..834] MSA 3.123933 View MSA. No confident structure predictions are available.
    3 View Details [835..902] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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