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Protein Overview: FLO5

General Information:
Name(s) found: FLO5 / YHR211W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1075 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed article][TASLink to PubMed article]
    Biological Process: flocculation via cell wall protein-carbohydrate interaction [IGILink to PubMed article]
    Molecular Function: mannose binding [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIAHHCIFL VILAFLALIN VASGATEACL PAGQRKSGMN INFYQYSLKD SSTYSNAAYM  60
   61 AYGYASKTKL GSVGGQTDIS IDYNIPCVSS SGTFPCPQED SYGNWGCKGM GACSNSQGIA 120
  121 YWSTDLFGFY TTPTNVTLEM TGYFLPPQTG SYTFSFATVD DSAILSVGGS IAFECCAQEQ 180
  181 PPITSTNFTI NGIKPWDGSL PDNITGTVYM YAGYYYPLKV VYSNAVSWGT LPISVELPDG 240
  241 TTVSDNFEGY VYSFDDDLSQ SNCTIPDPSI HTTSTITTTT EPWTGTFTST STEMTTITDT 300
  301 NGQLTDETVI VIRTPTTAST ITTTTEPWTG TFTSTSTEMT TVTGTNGQPT DETVIVIRTP 360
  361 TSEGLITTTT EPWTGTFTST STEMTTVTGT NGQPTDETVI VIRTPTSEGL ITTTTEPWTG 420
  421 TFTSTSTEVT TITGTNGQPT DETVIVIRTP TSEGLITTTT EPWTGTFTST STEMTTVTGT 480
  481 NGQPTDETVI VIRTPTSEGL ISTTTEPWTG TFTSTSTEVT TITGTNGQPT DETVIVIRTP 540
  541 TSEGLITTTT EPWTGTFTST STEMTTVTGT NGQPTDETVI VIRTPTSEGL ITRTTEPWTG 600
  601 TFTSTSTEVT TITGTNGQPT DETVIVIRTP TTAISSSLSS SSGQITSSIT SSRPIITPFY 660
  661 PSNGTSVISS SVISSSVTSS LVTSSSFISS SVISSSTTTS TSIFSESSTS SVIPTSSSTS 720
  721 GSSESKTSSA SSSSSSSSIS SESPKSPTNS SSSLPPVTSA TTGQETASSL PPATTTKTSE 780
  781 QTTLVTVTSC ESHVCTESIS SAIVSTATVT VSGVTTEYTT WCPISTTETT KQTKGTTEQT 840
  841 KGTTEQTTET TKQTTVVTIS SCESDICSKT ASPAIVSTST ATINGVTTEY TTWCPISTTE 900
  901 SKQQTTLVTV TSCESGVCSE TTSPAIVSTA TATVNDVVTV YPTWRPQTTN EQSVSSKMNS 960
  961 ATSETTTNTG AAETKTAVTS SLSRFNHAET QTASATDVIG HSSSVVSVSE TGNTMSLTSS1020
 1021 GLSTMSQQPR STPASSMVGS STASLEISTY AGSANSLLAG SGLSVFIASL LLAII

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) FLO1 FLO10 FLO5 FLO9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen FLO5 YDR131C 2 Unpublished Fields Lab Data
    View Screen FLO5 LOH1 2 Unpublished Fields Lab Data
    View Screen FLO5 SMA1 2 Unpublished Fields Lab Data
    View Screen FLO5 CCT4 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..250] MSA 2.121993 View MSA. No confident structure predictions are available.
    2 View Details [251..316] Pfam 20.060481 Flocculin repeat No confident structure predictions are available.
    3 View Details [317..361] Pfam 23.29243 Flocculin repeat No confident structure predictions are available.
    4 View Details [362..406] Pfam 23.522879 Flocculin repeat No confident structure predictions are available.
    5 View Details [407..451] Pfam 22.657577 Flocculin repeat No confident structure predictions are available.
    6 View Details [452..496] Pfam 23.522879 Flocculin repeat No confident structure predictions are available.
    7 View Details [497..541] Pfam 22.920819 Flocculin repeat No confident structure predictions are available.
    8 View Details [542..586] Pfam 23.522879 Flocculin repeat No confident structure predictions are available.
    9 View Details [587..646] Pfam 22.124939 Flocculin repeat No confident structure predictions are available.
    10 View Details [647..1075] MSA 5.193996 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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