Protein Overview: PFS1

General Information:
Name(s) found:	PFS1 / YHR185C [SGD]
Description(s) found: Found 26 descriptions. SHOW ALL	Sporulation protein required for prospore membrane formation at selected spindle poles, ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation [SGD]
Organism:	Saccharomyces cerevisiae
Length:	237 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	ascospore wall assembly [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQGYTQLSA PELKETKTSK LNKMNNFRSS PIAEIINKIP PDCGKIQNTT FPEFNPALRR  60
   61 RQHEQWPAYE KPIRVTDSMS PQLSSINCLP NLYPHGTLPL PNPYLSYLNH IEKVNCQDVK 120
  121 FSNWSVLHNS NNGFEIPTYF SPRTTQNMPC SEKVESWLER LPIFVGFDGY LFTNCFDYEY 180
  181 MLDWEETEFT FEKTSCMETD YSKALTDTDI IYIQEKKIEA LIRNQYLKEY EFSQKDF

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		CPR5 MDH3 PFS1 YDR248C YHL008C YHR097C

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	NAS2	PFS1	2	Uetz P, et al. (2000)
View Screen	RRP17	PFS1	1	Unpublished Fields Lab Data
View Screen	SPO13	PFS1	1	Uetz P, et al. (2000)
View Screen	HMG1	PFS1	1	Unpublished Fields Lab Data
View Screen	HMG1	PFS1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..237]	deduced	N/A	No confident structure predictions are available.
2	View Details	[132..237]	MSA	2.004991	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2