YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: PCL5

General Information:
Name(s) found: PCL5 / YHR071W [SGD]
Description(s) found:
Found 26 descriptions.
SHOW ALL
  • Cyclin, interacts with and phosphorylated by Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 229 amino acids

    Gene Ontology:
    Cellular Component: cyclin-dependent protein kinase holoenzyme complex [TASLink to PubMed article]
    Biological Process: cell cycle [TASLink to PubMed article]
    Molecular Function: cyclin-dependent protein kinase regulator activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGNHRFTPD SKEFNTVVKS KESSTGRNPY QTPPLEHNGT HHQTNYSRKK TNLAIIISNF  60
   61 LSEISRPLSN GKINNSTHNI LKFLNEVLKR SKCSKENAVL ATFYFQKIHQ SRGVRDESSL 120
  121 PEFSHCSRRI FLCCLILSHK FLNDNTYSMK NWQIISGLHA KDLSLMERWC LGKLNYELAI 180
  181 PYDEFLLWET NTLMKAKLRV GTPANAPVKR PRESDNDYDA NSWKQIKSC

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CLG1 PCL1 PCL2 PCL5 PHO80

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PHO85 PCL5 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..229] PSI-BLAST 36.39794 Cyclin A

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cyclin-dependent protein kinase regulator activity
    		•  3.19553060844126 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  2.87088741581791 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.795846725429 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  2.6060225603832 bayes_pls_golite062009
  • binding
    		•  2.4204867358489 bayes_pls_golite062009
  • DNA binding
    		•  1.94297811210385 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.74388377119212 bayes_pls_golite062009
  • kinase regulator activity
    		•  1.65109787211976 bayes_pls_golite062009
  • protein binding
    		•  1.47106731485576 bayes_pls_golite062009
  • transcription factor activity
    		•  1.21921365719206 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.09952334871968 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.90568770487799 bayes_pls_golite062009
  • transcription factor binding
    		•  0.749278791251235 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.729629809946521 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0696060248241566 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle