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Protein Overview: MGA1

General Information:
Name(s) found: MGA1 / YGR249W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 456 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    Biological Process: filamentous growth [IGILink to PubMed article]
    Molecular Function: DNA binding [IDALink to PubMed article]
    transcription factor activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPKTFVHQL HAILLEPEVN KWIYWSPTDN TVFFLKPYDP NFSTHVLKRY FKHGNVNSFV  60
   61 RQLHMYGFHK LSHPSPDQSS ANNGNVKELV EWKFTHPSGF FFKEANAGIL NKIQRKSTGV 120
  121 GKDGKRKNIL SPISVSYVDA SRLNVLSQQS GPVSAREPSN MFMGSPVHYS TSQSPPHISI 180
  181 PQQQQSSGPY LISSLPPQQP TVNMMRRQSI SARMMNSYDY PNQFSTQDSI VQPQQPQQVL 240
  241 SPQALSGPPM KKSGTLSSTD DLKTTSLPIV NYPMPYHPGA FAQQQQQQQQ PLPTVPPYSS 300
  301 YSTPFPSMMN SLSNSASNSP ALGVCNNNVT LPKKSNISER QALDNHIQTL KNSLSTITDL 360
  361 IEKHINSASQ DENKTLTNDA MNKDLRTSLS LLQNSKEEII QLESKWMSMQ SVKTTALPLQ 420
  421 ETTNTSSTLT SLTSSIIPKS IPIITKGEVA TKPASY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..117] PSI-BLAST 129.70927 Heat-shock transcription factor
    2 View Details [118..456] ORFEUS 14.93 RBP1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  2.69048535857291 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.64324711228084 bayes_pls_golite062009
  • DNA binding
    		•  2.61442118042246 bayes_pls_golite062009
  • binding
    		•  2.37880408751912 bayes_pls_golite062009
  • transcription factor activity
    		•  1.88900792328916 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.68922344928172 bayes_pls_golite062009
  • transcription activator activity
    		•  0.485327753327262 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.385147412723772 bayes_pls_golite062009
  • protein binding
    		•  0.35301104350965 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle