YRC Public Data Repository - Protein Structure Prediction

Protein:	MGA1
Organism:	Saccharomyces cerevisiae
Length:	456 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MGA1.

Description	E-value	Query Range	Subject Range
gi\|17390978 - gi\|17390978\|gb\|AAH18414.1\| Hsf2 protein [Mus musculus]	0.0	[4..439]	[8..457]
gi\|13928966, gi\|... - gi\|5764553\|gb\|AAD51329.1\|AF172640_1 heat shock factor 2 [Rattus norvegicus], gi\|55778284\|gb\|AAH86554...	0.0	[4..439]	[8..453]
HSF1 - heat shock transcription factor 1 gi\|61362382, gi\|... - gi\|61362386\|gb\|AAX42211.1\| heat shock transcription factor 1 [synthetic construct], gi\|61362382\|gb\|A...	0.0	[4..433]	[16..485]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	0.0	[4..433]	[16..485]
HSF1_CHICK - Heat shock factor protein 1 OS=Gallus gallus GN=HSF1 PE=2 SV=1	0.0	[5..432]	[22..448]
gi\|17061843 - gi\|17061843\|dbj\|BAB72171.1\| heat shock transcription factor [Danio rerio]	0.0	[4..428]	[19..458]
gi\|17061845 - gi\|17061845\|dbj\|BAB72172.1\| heat shock transcription factor with His-tag [synthetic construct]	0.0	[4..428]	[19..458]

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Predicted Domain #1

Region A:
Residues: [1-117]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPKTFVHQL HAILLEPEVN KWIYWSPTDN TVFFLKPYDP NFSTHVLKRY FKHGNVNSFV  60
   61 RQLHMYGFHK LSHPSPDQSS ANNGNVKELV EWKFTHPSGF FFKEANAGIL NKIQRKS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	129.70927
Match:	1hks__
Description:	Heat-shock transcription factor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.69048535857291	bayes_pls_golite062009
nucleic acid binding	2.64324711228084	bayes_pls_golite062009
DNA binding	2.61442118042246	bayes_pls_golite062009
binding	2.37880408751912	bayes_pls_golite062009
transcription factor activity	1.88900792328916	bayes_pls_golite062009
sequence-specific DNA binding	0.68922344928172	bayes_pls_golite062009
transcription activator activity	0.485327753327262	bayes_pls_golite062009
transcription repressor activity	0.385147412723772	bayes_pls_golite062009
protein binding	0.35301104350965	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [118-456]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGVGKDGKRK NILSPISVSY VDASRLNVLS QQSGPVSARE PSNMFMGSPV HYSTSQSPPH  60
   61 ISIPQQQQSS GPYLISSLPP QQPTVNMMRR QSISARMMNS YDYPNQFSTQ DSIVQPQQPQ 120
  121 QVLSPQALSG PPMKKSGTLS STDDLKTTSL PIVNYPMPYH PGAFAQQQQQ QQQPLPTVPP 180
  181 YSSYSTPFPS MMNSLSNSAS NSPALGVCNN NVTLPKKSNI SERQALDNHI QTLKNSLSTI 240
  241 TDLIEKHINS ASQDENKTLT NDAMNKDLRT SLSLLQNSKE EIIQLESKWM SMQSVKTTAL 300
  301 PLQETTNTSS TLTSLTSSII PKSIPIITKG EVATKPASY

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	14.93
Match:	1i3qA
Description:	RBP1
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: