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Protein Overview: ATF2

General Information:
Name(s) found: ATF2 / YGR177C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Alcohol acetyltransferase, may play a role in steroid detoxification; forms volatile esters during fermentation, which is important for brewing and winemaking [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 535 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: steroid metabolic process [IMPLink to PubMed article]
    Molecular Function: alcohol O-acetyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDIEGYEPH ITQELIDRGH ARRMGHLENY FAVLSRQKMY SNFTVYAELN KGVNKRQLML  60
   61 VLKVLLQKYS TLAHTIIPKH YPHHEAYYSS EEYLSKPFPQ HDFIKVISHL EFDDLIMNNQ 120
  121 PEYREVMEKI SEQFKKDDFK VTNRLIELIS PVIIPLGNPK RPNWRLICLP GKDTDGFETW 180
  181 KNFVYVTNHC GSDGVSGSNF FKDLALLFCK IEEKGFDYDE EFIEDQVIID YDRDYTEISK 240
  241 LPKPITDRID YKPALTSLPK FFLTTFIYEH CNFKTSSEST LTARYSPSSN ANASYNYLLH 300
  301 FSTKQVEQIR AQIKKNVHDG CTLTPFIQAC FLVALYRLDK LFTKSLLEYG FDVAIPSNAR 360
  361 RFLPNDEELR DSYKYGSNVG GSHYAYLISS FDIPEGDNDK FWSLVEYYYD RFLESYDNGD 420
  421 HLIGLGVLQL DFIVENKNID SLLANSYLHQ QRGGAIISNT GLVSQDTTKP YYVRDLIFSQ 480
  481 SAGALRFAFG LNVCSTNVNG MNMDMSVVQG TLRDRGEWES FCKLFYQTIG EFASL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ATF2 YGR130C YMR031C
    View Details Qiu et al. (2008) ARE1 ATF2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #13 Mitotic Prep2-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ATF2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] deduced N/A No confident structure predictions are available.
    2 View Details [121..535] MSA 1.005902 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acyltransferase activity
    		•  2.59651247599228 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  2.54185972075515 bayes_pls_golite062009
  • S-acyltransferase activity
    		•  2.14752294017541 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  2.03684539755503 bayes_pls_golite062009
  • dihydrolipoyllysine-residue succinyltransferase activity
    		•  1.64228557237371 bayes_pls_golite062009
  • S-succinyltransferase activity
    		•  1.64228557237371 bayes_pls_golite062009
  • dihydrolipoamide S-acyltransferase activity
    		•  1.63157954715285 bayes_pls_golite062009
  • dihydrolipoyllysine-residue acetyltransferase activity
    		•  1.51548011652574 bayes_pls_golite062009
  • S-acetyltransferase activity
    		•  1.49282602406988 bayes_pls_golite062009
  • carnitine O-acyltransferase activity
    		•  1.47327319537751 bayes_pls_golite062009
  • catalytic activity
    		•  1.4057670600405 bayes_pls_golite062009
  • palmitoyltransferase activity
    		•  1.3874981953191 bayes_pls_golite062009
  • transferase activity
    		•  0.831981508678452 bayes_pls_golite062009
  • binding
    		•  0.464558006194551 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  0.225376815398512 bayes_pls_golite062009
  • O-palmitoyltransferase activity
    		•  0.150321891635568 bayes_pls_golite062009
  • carnitine O-palmitoyltransferase activity
    		•  0.150321891635568 bayes_pls_golite062009
  • ligase activity
    		•  0.135311204595182 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle