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Protein Overview: YGR122W

General Information:
Name(s) found: YGR122W [SGD]
Description(s) found:
Found 31 descriptions.
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  • Probable ortholog of A. nidulans PalC, which is involved in pH regulation and binds to the ESCRT-III complex; null mutant does not properly process Rim101p and has decreased resistance to rapamycin; GFP-fusion protein is cytoplasmic [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 402 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRENAMSTKK LPYKLSGSSK ITTSIPNDLI ILRNNCINSL NSSSSKADSI TCIDTWLKYT  60
   61 EGLLTHRYEA NNDAALIEEE IAIALINVAV FYQDIGIETL YRAYESSQAS NNLWTTSGTY 120
  121 LKRGLGLICF LGKNFQINTA NDCQKMQVLN VLNQLSLEFQ LLQQLGIVVL ALSKLRSKIS 180
  181 KDAVADLEPQ ELEELGKSSV FYAKLCIGSY STASQCQGGR IVDALFMNYL QSLTYLFLSI 240
  241 NQYNNDECGI AIGMLQESIK KLLNIVPNSQ LKELDILSST DITKKRDLIK MSFKRKIHGS 300
  301 TLKNQRIFEK KVPFSSKAYM MPLLKSSLDD FVIPLTILLR YRYQTTNENY SFKTVETDVS 360
  361 KLKELFPRGK SSDIEGTVWS FQDGHLTFAD SNNATHNCGN YF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YGR122W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..402] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle