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Protein Overview: COG2

General Information:
Name(s) found: COG2 / YGR120C [SGD]
Description(s) found:
Found 16 descriptions.
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  • Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 275 amino acids

    Gene Ontology:
    Cellular Component: Golgi transport complex [IPILink to PubMed article]
    soluble fraction [IDALink to PubMed article]
    peripheral to membrane of membrane fraction [IDALink to PubMed article]
    Biological Process: ER to Golgi vesicle-mediated transport [IGILink to PubMed article]
    intra-Golgi vesicle-mediated transport [IGILink to PubMed article][IPILink to PubMed article]
    retrograde transport, vesicle recycling within Golgi [IMPLink to PubMed article][TASLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNSHSRNFS QGEMDFLNDD ELDLDLPVTA EISKELFATE IEKYRESETN GTDVDNFDVD  60
   61 RFLVQKNFHY LPLDSLIRDL SGLSQKMVQT LLEQIRSNYD DYLTFSNTYT DEENETLINL 120
  121 EKTQSDLQKF MTQLDHLIKD DISNTQEIIK DVLEYLKKLD EIYGSLRNHS QLTEALSLGK 180
  181 RLSKSLHEMC GIEPLEEEIC SGLIEQLYKL ITASRRILES CADSNSPYIH HLRNDYQDLL 240
  241 QEFQISLKIL TEKCLENPSS LQNLSLTLVS IIKTA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..275] ORFEUS 7.49 Son of sevenless protein homolog 1 (sos-1)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle