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Protein Overview: MTL1

General Information:
Name(s) found: MTL1 / YGR023W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Putative plasma membrane sensor, involved in cell integrity signaling and stress response during glucose starvation and oxidative stress; has structural and functional similarity to Mid2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 551 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [ISSLink to PubMed article]
    Biological Process: cellular cell wall organization [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASCNPTRKK SSASSLSMWR TILMALTTLP LSVLSQELVP ANSTTSSTAP SITSLSAVES  60
   61 FTSSTDATSS ASLSTPSIAS VSFTSFPQSS SLLTLSSTLS SELSSSSMQV SSSSTSSSSS 120
  121 EVTSSSSSSS ISPSSSSSTI ISSSSSLPTF TVASTSSTVA SSTLSTSSSL VISTSSSTFT 180
  181 FSSESSSSLI SSSISTSVST SSVYVPSSST SSPPSSSSEL TSSSYSSSSS SSTLFSYSSS 240
  241 FSSSSSSSSS SSSSSSSSSS SSSSYFTLST SSSSSIYSSS SYPSFSSSSS SNPTSSITST 300
  301 SASSSITPAS EYSNLAKTIT SIIEGQTILS NYYTTITYSP TASASSGKNS HHSGLSKKNR 360
  361 NIIIGCVVGI GAPLILILLI LIYMFCVQPK KTDFIDSDGK IVTAYRSNIF TKIWYFLLGK 420
  421 KIGETERFSS DSPIGSNNIQ NFGDIDPEDI LNNDNPYTPK HTNVEGYDDD DDDDANDENL 480
  481 SSNFHNRGID DQYSPTKSAS YSMSNSNSQD YNDADEVMHD ENIHRVYDDS EASIDENYYT 540
  541 KPNNGLNITN Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 3908: TAP-tagged, includes hir2(delta) in background Green EM, et al (2005)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..70] deduced N/A No confident structure predictions are available.
    2 View Details [71..134] ab initio 12.15 No description for 1deqA was found.
    3 View Details [135..388] ab initio 14.43 No description for 1m2vB was found.
    4 View Details [389..551] MSA 1.146996 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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