YRC Public Data Repository - Protein Structure Prediction

Protein:	MTL1
Organism:	Saccharomyces cerevisiae
Length:	551 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTL1.

Description	E-value	Query Range	Subject Range
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1	257.0	[0..12]	[506..599]
gi\|70869911 - gi\|70869911\|gb\|EAN84377.1\| trans-sialidase, putative [Trypanosoma cruzi] gi\|71407532 - gi\|71407532\|ref\|XP_806228.1\| trans-sialidase [Trypanosoma cruzi strain CL Brener]	242.0	[0..15]	[506..667]
gi\|15828996 - gi\|15828996\|ref\|NP_326356.1\| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP] gi\|14089939, gi\|... - pir\|\|E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi\|14089...	238.0	[0..2]	[510..116]
gi\|9695347 - gi\|9695347\|gb\|AAF97432.1\|U23947_9 VsaC1 [Mycoplasma pulmonis]	216.0	[0..2]	[451..55]
gi\|4808166 - gi\|4808166\|emb\|CAB42797.1\| largest subunit of the RNA polymerase II complex [Drosophila pseudoobscur...	211.0	[0..1]	[309..1446]
gi\|9587193, gi\|9... - gi\|9587199\|gb\|AAF89203.1\|AF272653_1 RNA polymerase II largest subunit [Drosophila subobscura], gi\|95...	195.0	[0..1]	[308..1524]
gi\|71064076 - gi\|71064076\|gb\|AAZ22486.1\| Mtl1p [Saccharomyces cerevisiae]	193.0	[0..414]	[551..1]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...	188.0	[0..4]	[508..868]
gi\|33310026 - gi\|33310026\|gb\|AAQ03243.1\|AF414112_1 putative cell wall protein FLO11p [Candida albicans] gi\|68482880, gi\|... - gi\|68482880\|ref\|XP_714666.1\| putative cell wall adhesin [Candida albicans SC5314], gi\|46436253\|gb\|EA...	183.0	[0..11]	[508..179]
gi\|11385307 - gi\|11385307\|pir\|\|A35175 mucin 1 precursor, repetitive splice form A [validated] - human	183.0	[0..1]	[486..547]

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Predicted Domain #1

Region A:
Residues: [1-70]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASCNPTRKK SSASSLSMWR TILMALTTLP LSVLSQELVP ANSTTSSTAP SITSLSAVES  60
   61 FTSSTDATSS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [71-134]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASLSTPSIAS VSFTSFPQSS SLLTLSSTLS SELSSSSMQV SSSSTSSSSS EVTSSSSSSS  60
   61 ISPS

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	12.15
Match:
Description:	No description for 1deqA was found.

Predicted Domain #3

Region A:
Residues: [135-388]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSTIISSS SSLPTFTVAS TSSTVASSTL STSSSLVIST SSSTFTFSSE SSSSLISSSI  60
   61 STSVSTSSVY VPSSSTSSPP SSSSELTSSS YSSSSSSSTL FSYSSSFSSS SSSSSSSSSS 120
  121 SSSSSSSSSS YFTLSTSSSS SIYSSSSYPS FSSSSSSNPT SSITSTSASS SITPASEYSN 180
  181 LAKTITSIIE GQTILSNYYT TITYSPTASA SSGKNSHHSG LSKKNRNIII GCVVGIGAPL 240
  241 ILILLILIYM FCVQ

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	14.43
Match:
Description:	No description for 1m2vB was found.

Predicted Domain #4

Region A:
Residues: [389-551]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKKTDFIDSD GKIVTAYRSN IFTKIWYFLL GKKIGETERF SSDSPIGSNN IQNFGDIDPE  60
   61 DILNNDNPYT PKHTNVEGYD DDDDDDANDE NLSSNFHNRG IDDQYSPTKS ASYSMSNSNS 120
  121 QDYNDADEVM HDENIHRVYD DSEASIDENY YTKPNNGLNI TNY

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits