YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: PRP18

General Information:
Name(s) found: PRP18 / YGR006W [SGD]
Description(s) found:
Found 9 descriptions.
SHOW ALL
  • Splicing factor involved in the positioning of the 3' splice site during the second catalytic step of splicing, part of snRNP U5, interacts with Slu7p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 219 amino acids

    Gene Ontology:
    Cellular Component: U4/U6 x U5 tri-snRNP complex [TASLink to PubMed article]
    spliceosomal complex [IDALink to PubMed article]
    Biological Process: generation of catalytic spliceosome for second transesterification step [IDALink to PubMed article]
    nuclear mRNA splicing, via spliceosome [IMPLink to PubMed article]
    Molecular Function: second spliceosomal transesterification activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLDLASILK GEISKKKKEL ANSKGVQPPC TEKFQPHESA NIDETPRQVE QESTDEENLS  60
   61 DNQSDDIRTT ISKLENRPER IQEAIAQDKT ISVIIDPSQI GSTEGKPLLS MKCNLYIHEI 120
  121 LSRWKASLEA YHPELFLDTK KALFPLLLQL RRNQLAPDLL ISLATVLYHL QQPKEINLAV 180
  181 QSYMKLSIGN VAWPIGVTSV AFMLVVHIRK FKEAGMLLT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..78] deduced N/A No confident structure predictions are available.
    2 View Details [79..219] PSI-BLAST 619.70927 Functional domain of the splicing factor Prp18


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle