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Protein Overview: AML1

General Information:
Name(s) found: AML1 / YGR001C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Putative protein of unknown function with similarity to methyltransferase family members; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; required for replication of Brome mosaic virus in S. cerevisiae [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 248 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSDSDSDY ELTLSANALA ALEEFKREEQ QHQEAFQKLY DETDEDFQKK KKEEGMKLFK  60
   61 EDWQLSQFWY SDDTAAILAD AILEGADENT VIAIVSAPSV YAAIQKKPTN EIPTEHIYLF 120
  121 EFDKRFELLA GRDHFFFYDY NKPLDFSDEI KGKVDRLLID PPFLNEDCQT KSSITAKCLL 180
  181 APNDNSKTKK GVFKHRLISC TGERMSEVIS KVYSDTRITT FLPEHSNGLS NEFRCYANFE 240
  241 CSSWKFAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen AML1 OAF3 2 Unpublished Fields Lab Data
    View Screen AML1 YIL029C 1 Unpublished Fields Lab Data
    View Screen AML1 GSM1 1 Unpublished Fields Lab Data
    View Screen AML1 ENT4 1 Unpublished Fields Lab Data
    View Screen AML1 RNP1 1 Unpublished Fields Lab Data
    View Screen AML1 RSN1 1 Unpublished Fields Lab Data
    View Screen AML1 VPS8 1 Unpublished Fields Lab Data
    View Screen AML1 GCR2 1 Unpublished Fields Lab Data
    View Screen AML1 CCR4 1 Unpublished Fields Lab Data
    View Screen AML1 SAM3 1 Unpublished Fields Lab Data
    View Screen AML1 HSP26 1 Unpublished Fields Lab Data
    View Screen AML1 RPO26 1 Unpublished Fields Lab Data
    View Screen AML1 RRT12 1 Unpublished Fields Lab Data
    View Screen AML1 YPR197C 1 Unpublished Fields Lab Data
    View Screen AML1 TRM8 1 Unpublished Fields Lab Data
    View Screen AML1 CDC13 1 Unpublished Fields Lab Data
    View Screen AML1 YGL024W 1 Unpublished Fields Lab Data
    View Screen AML1 HAH1 1 Unpublished Fields Lab Data
    View Screen AML1 FMP43 1 Unpublished Fields Lab Data
    View Screen AML1 RPL42B, RPL42A 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data AML1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..248] FFAS03 0.963 Crystal Structure of Putative Methylase from Enterococcus faecalis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.16970557486814 bayes_pls_golite062009
  • transferase activity
    		•  0.822796502536128 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.612864078793564 bayes_pls_golite062009
  • DNA binding
    		•  0.590883316793444 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.495242738476094 bayes_pls_golite062009
  • binding
    		•  0.439311894979003 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.356820770014331 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.181009652174389 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.165326524526999 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle