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Protein Overview: HNM1

General Information:
Name(s) found: HNM1 / YGL077C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 563 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: choline transport [IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: choline transmembrane transporter activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIRNDNASG GYMQPDQSSN ASMHKRDLRV EEEIKPLDDM DSKGAVAADG EVHLRKSFSL  60
   61 WSILGVGFGL TNSWFGISTS MVAGISSGGP MMIVYGIIIV ALISICIGTS LGELSSAYPH 120
  121 AGGQFWWSLK LAPPKYKRFA AYMCGSFAYA GSVFTSASTT LSVATEVVGM YALTHPEFIP 180
  181 KRWHIFVCFE LLHLFLMFFN CYGKSLPIIS SSSLYISLLS FFTITITVLA CSHGKFNDAK 240
  241 FVFATFNNET GWKNGGIAFI VGLINPAWSF SCLDCATHMA FEVEKPERVI PIAIMGTVAI 300
  301 GFVTSFCYVI AMFFSIQDLD AVLSSTTGAP ILDIYNQALG NKSGAIFLGC LILFTSFGCV 360
  361 IACHTWQARL CWSFARDNGL PLSRLWSQVN PHTGVPLNAH LMSCAWITLI GLLYLASSTA 420
  421 FQSLITGCIA FLLLSYIIPV ICLLAKKRNI AHGPFWLGKF GFFSNIVLLG WTVFSVVFFS 480
  481 FPPVLPVTKD NMNYVCVVIV GYTAYSILYW KYKGKKEFHA LEESENEQAE YSNNFDTIED 540
  541 SREFSVAASD VELENEHVPW GKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) DIP5 HNM1 TPO3

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data HNM1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..563] Pfam 7.086186 Amino acid permease No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle