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Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive the transport of choline across a membrane. Catalysis of the transfer of choline from one side of the membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other. Catalysis of the transfer of amines, including polyamines, from one side of the membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in). Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: choline transmembrane transporter activity
Acc: GO:0015220
Aspect: Molecular Function
Desc: Catalysis of the transfer of choline from one side of the membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
Synonyms:
  • GO:0005306
  • choline permease activity
  • amino acid/choline transmembrane transporter activity
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015220 - choline transmembrane transporter activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle