YRC Public Data Repository - Protein Structure Prediction

Protein:	HNM1
Organism:	Saccharomyces cerevisiae
Length:	563 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HNM1.

Description	E-value	Query Range	Subject Range
gi\|190407034 - gi\|190407034\|gb\|EDV10301.1\| choline transport protein [Saccharomyces cerevisiae RM11-1a] gi\|151943730 - gi\|151943730\|gb\|EDN62040.1\| choline transporter [Saccharomyces cerevisiae YJM789] HNM1 - Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glyci... HNM1_YEAST - Choline transport protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HNM1 PE=1 SV=1	9.0E-92	[1..563]	[1..563]
YI26_SCHPO - Uncharacterized amino-acid permease P7G5.06 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G... SPAP7G5.06 - amino acid permease, unknown 4	2.0E-88	[2..516]	[22..542]
gi\|68470470, gi\|... - gi\|68470731\|ref\|XP_720611.1\| N-acetylglucosamine-inducible general amino acid permease [Candida albi... gi\|18568390 - gi\|18568390\|gb\|AAL76065.1\| Gap1 protein [Candida albicans] gi\|238882678 - gi\|238882678\|gb\|EEQ46316.1\| general amino-acid permease GAP1 [Candida albicans WO-1]	3.0E-84	[32..545]	[49..561]
gi\|165936285, gi... - gi\|89104688\|ref\|ZP_01177224.1\| COG0833: Amino acid transporters [Yersinia pestis biovar Orientalis s... gi\|108807022, gi... - gi\|108807022\|ref\|YP_650938.1\| lysine transporter [Yersinia pestis Antiqua], gi\|108778935\|gb\|ABG12993... gi\|229679023, gi... - gi\|229903253\|ref\|ZP_04518366.1\| lysine transporter [Yersinia pestis Nepal516], gi\|229679023\|gb\|EEO75... Q66CR2\|Q66CR2_YERPS - Lysine-specific permease lysP, APC family precursor - Yersinia pseudotuberculosis gi\|166009838, gi... - gi\|166009838\|ref\|ZP_02230736.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. E... gi\|165924474, gi... - gi\|165924474\|ref\|ZP_02220306.1\| lysine-specific permease LysP [Yersinia pestis biovar Orientalis str... gi\|167400403, gi... - gi\|167400403\|ref\|ZP_02305916.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. U... gi\|166211768, gi... - gi\|166211768\|ref\|ZP_02237803.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. B... gi\|167424094, gi... - gi\|167424094\|ref\|ZP_02315847.1\| lysine-specific permease LysP [Yersinia pestis biovar Mediaevalis st... gi\|167419868, gi... - gi\|167419868\|ref\|ZP_02311621.1\| lysine-specific permease LysP [Yersinia pestis biovar Orientalis str... gi\|186894753, gi... - gi\|186894753\|ref\|YP_001871865.1\| lysine transporter [Yersinia pseudotuberculosis PB1/+], gi\|18669777... gi\|170024977, gi... - gi\|170024977\|ref\|YP_001721482.1\| lysine transporter [Yersinia pseudotuberculosis YPIII], gi\|16975151... gi\|229841266, gi... - gi\|229841266\|ref\|ZP_04461425.1\| lysine transporter [Yersinia pestis biovar Orientalis str. PEXU2], g... gi\|229843369, gi... - gi\|229843369\|ref\|ZP_04463515.1\| lysine transporter [Yersinia pestis biovar Orientalis str. India 195... gi\|229895742, gi... - gi\|229895742\|ref\|ZP_04510912.1\| lysine transporter [Yersinia pestis Pestoides A], gi\|229700665\|gb\|EE... gi\|149366712, gi... - gi\|149366712\|ref\|ZP_01888746.1\| putative lysine-specific permease [Yersinia pestis CA88-4125], gi\|14... gi\|145599660, gi... - gi\|145599660\|ref\|YP_001163736.1\| lysine transporter [Yersinia pestis Pestoides F], gi\|145211356\|gb\|A... gi\|25296480 - pir\|\|AH0159 probable lysine-specific permease lysP [imported] - Yersinia pestis (strain CO92) gi\|45435969, gi\|... - gi\|45441110\|ref\|NP_992649.1\| lysine transporter [Yersinia pestis biovar Microtus str. 91001], gi\|454... gi\|22126753, gi\|... - gi\|22126753\|ref\|NP_670176.1\| lysine transporter [Yersinia pestis KIM], gi\|21959776\|gb\|AAM86427.1\|AE0... gi\|218928459, gi... - gi\|218928459\|ref\|YP_002346334.1\| lysine transporter [Yersinia pestis CO92], gi\|16121591\|ref\|NP_40490... gi\|51595681, gi\|... - gi\|51595681\|ref\|YP_069872.1\| lysine transporter [Yersinia pseudotuberculosis IP 32953], gi\|51588963\|... gi\|162353225, gi... - gi\|77634357\|ref\|ZP_00796459.1\| COG0833: Amino acid transporters [Yersinia pestis Angola], gi\|1624204... gi\|153948146, gi... - gi\|77632298\|ref\|ZP_00794884.1\| COG0833: Amino acid transporters [Yersinia pseudotuberculosis IP 3175...	1.0E-83	[42..516]	[5..478]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	2.0E-82	[4..544]	[32..589]

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Predicted Domain #1

Region A:
Residues: [1-563]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIRNDNASG GYMQPDQSSN ASMHKRDLRV EEEIKPLDDM DSKGAVAADG EVHLRKSFSL  60
   61 WSILGVGFGL TNSWFGISTS MVAGISSGGP MMIVYGIIIV ALISICIGTS LGELSSAYPH 120
  121 AGGQFWWSLK LAPPKYKRFA AYMCGSFAYA GSVFTSASTT LSVATEVVGM YALTHPEFIP 180
  181 KRWHIFVCFE LLHLFLMFFN CYGKSLPIIS SSSLYISLLS FFTITITVLA CSHGKFNDAK 240
  241 FVFATFNNET GWKNGGIAFI VGLINPAWSF SCLDCATHMA FEVEKPERVI PIAIMGTVAI 300
  301 GFVTSFCYVI AMFFSIQDLD AVLSSTTGAP ILDIYNQALG NKSGAIFLGC LILFTSFGCV 360
  361 IACHTWQARL CWSFARDNGL PLSRLWSQVN PHTGVPLNAH LMSCAWITLI GLLYLASSTA 420
  421 FQSLITGCIA FLLLSYIIPV ICLLAKKRNI AHGPFWLGKF GFFSNIVLLG WTVFSVVFFS 480
  481 FPPVLPVTKD NMNYVCVVIV GYTAYSILYW KYKGKKEFHA LEESENEQAE YSNNFDTIED 540
  541 SREFSVAASD VELENEHVPW GKK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	7.086186
Match:	PF00324
Description:	Amino acid permease

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits