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Protein Overview: TYW3

General Information:
Name(s) found: TYW3 / YGL050W [SGD]
Description(s) found:
Found 33 descriptions.
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  • tRNA methyltransferase required for synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 273 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAQNAFEQK KRAILNEIDS TQPDLSPKGT IDELCLPIID LINASADMVT TSSCSGRVSV  60
   61 FLEGTKSYNG EVKIGGKGQG GKWLYVTHDR EKVIGWLDEL KSKSEFSFEL SGKEIPTEKV 120
  121 TGSIRYILYK YEPFILHVKC RDFQAASKLY NTAMSCGFRE SGIGSNNLVA IRINIKLDVP 180
  181 LGYLDETSGT LKFFVTPEYV SVLDSLSLSK FDENTRKMQA LYDRIEKELI NCAPDVNSKV 240
  241 NITPIETKEE RRERKKREGM ERQRQLKSPQ NVL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) MTQ2 PCL7 TYW3

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen RAD1 TYW3 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..273] Pfam 155.017729 Uncharacterized ACR, COG1590 No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle