YRC Public Data Repository - Protein Structure Prediction

Protein:	TYW3
Organism:	Saccharomyces cerevisiae
Length:	273 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TYW3.

Description	E-value	Query Range	Subject Range
TYW3 - tRNA methyltransferase required for synthesis of wybutosine, a modified guanosine found at the 3'-po... TYW3_YEAST - tRNA wybutosine-synthesizing protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=T...	7.0E-97	[1..273]	[1..273]
TYW3_SCHPO - tRNA wybutosine-synthesizing protein 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tyw... SPAC25B8.15c - wybutosine biosynthesis protein Tyw3	5.0E-63	[6..229]	[9..217]
TYW23_ARATH - tRNA wybutosine-synthesizing protein 2/3/4 OS=Arabidopsis thaliana GN=At4g04670 PE=2 SV=1	1.0E-58	[7..225]	[3..208]
gi\|7518962 - gi\|7518962\|pir\|\|B71101 hypothetical protein PH1069 - Pyrococcus horikoshii gi\|3257485, gi\|1... - gi\|3257485\|dbj\|BAA30168.1\| 200aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14590905\|...	7.0E-54	[7..227]	[11..197]
Y917_PYRAB - UPF0130 protein PYRAB09170 OS=Pyrococcus abyssi GN=PYRAB09170 PE=3 SV=1 TYW31_PYRAB - tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1 OS=Pyrococcus...	1.0E-53	[7..227]	[7..193]
TYW31_PYRHO - tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1 OS=Pyrococcus... YA69_PYRHO, Y106... - (O58796) Hypothetical UPF0130 protein PH1069, UPF0130 protein PH1069 OS=Pyrococcus horikoshii GN=PH1...	2.0E-53	[7..227]	[7..193]
gi\|18978406, gi\|... - gi\|18978406\|ref\|NP_579763.1\| hypothetical protein PF2034 [Pyrococcus furiosus DSM 3638], gi\|18894246...	1.0E-49	[9..227]	[25..208]
Y1510_METJA, YF1... - (Q58905) Hypothetical UPF0130 protein MJ1510, UPF0130 protein MJ1510 OS=Methanocaldococcus jannaschi... TYW3_METJA - tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase OS=Methanocaldo...	8.0E-47	[8..227]	[5..190]

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Predicted Domain #1

Region A:
Residues: [1-273]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAQNAFEQK KRAILNEIDS TQPDLSPKGT IDELCLPIID LINASADMVT TSSCSGRVSV  60
   61 FLEGTKSYNG EVKIGGKGQG GKWLYVTHDR EKVIGWLDEL KSKSEFSFEL SGKEIPTEKV 120
  121 TGSIRYILYK YEPFILHVKC RDFQAASKLY NTAMSCGFRE SGIGSNNLVA IRINIKLDVP 180
  181 LGYLDETSGT LKFFVTPEYV SVLDSLSLSK FDENTRKMQA LYDRIEKELI NCAPDVNSKV 240
  241 NITPIETKEE RRERKKREGM ERQRQLKSPQ NVL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	155.017729
Match:	PF02676
Description:	Uncharacterized ACR, COG1590

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits