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Protein Overview: ALG13

General Information:
Name(s) found: ALG13 / YGL047W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Catalytic component of UDP-GlcNAc transferase, required for the second step of dolichyl-linked oligosaccharide synthesis; anchored to the ER membrane via interaction with Alg14p; similar to bacterial and human glycosyltransferases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 202 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDALink to PubMed article]
    nucleus [IDALink to PubMed article]
    extrinsic to endoplasmic reticulum membrane [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed articleLink to PubMed article]
    UDP-N-acetylglucosamine transferase complex [IPILink to PubMed articleLink to PubMed article]
    cytosol [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: dolichol-linked oligosaccharide biosynthetic process [IDALink to PubMed article][IMPLink to PubMed articleLink to PubMed article][ISSLink to PubMed articleLink to PubMed article]
    Molecular Function: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity [IDALink to PubMed article][IMPLink to PubMed articleLink to PubMed article][ISSLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIIEEKALF VTCGATVPFP KLVSCVLSDE FCQELIQYGF VRLIIQFGRN YSSEFEHLVQ  60
   61 ERGGQRESQK IPIDQFGCGD TARQYVLMNG KLKVIGFDFS TKMQSIIRDY SDLVISHAGT 120
  121 GSILDSLRLN KPLIVCVNDS LMDNHQQQIA DKFVELGYVW SCAPTETGLI AGLRASQTEK 180
  181 LKPFPVSHNP SFERLLVETI YS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ALG13 ALG14 ALG2 ALG6 DIE2 OST5 SHR5 STT3 WBP1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ALG13 No Comments Hazbun TR, et al. (2003)
    View Run ALG13 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ALG13 and SPC42 Hazbun TR, et al. (2003)
    View Data ALG13 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] PSI-BLAST 27.522879 Peptidoglycan biosynthesys glycosyltransferase MurG


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle