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Protein Overview: OCH1

General Information:
Name(s) found: OCH1 / YGL038C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 480 amino acids

    Gene Ontology:
    Cellular Component: Golgi cis cisterna [IDALink to PubMed articleLink to PubMed article]
    Biological Process: protein amino acid N-linked glycosylation [IMPLink to PubMed article]
    Molecular Function: transferase activity, transferring glycosyl groups [ISSLink to PubMed article]
    alpha-1,6-mannosyltransferase activity [IDALink to PubMed articleLink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKLSHLIA TRKSKTIVVT VLLIYSLLTF HLSNKRLLSQ FYPSKDDFKQ TLLPTTSHSQ  60
   61 DINLKKQITV NKKKNQLHNL RDQLSFAFPY DSQAPIPQRV WQTWKVGADD KNFPSSFRTY 120
  121 QKTWSGSYSP DYQYSLISDD SIIPFLENLY APVPIVIQAF KLMPGNILKA DFLRYLLLFA 180
  181 RGGIYSDMDT MLLKPIDSWP SQNKSWLNNI IDLNKPIPYK NSKPSLLSSD EISHQPGLVI 240
  241 GIEADPDRDD WSEWYARRIQ FCQWTIQAKP GHPILRELIL NITATTLASV QNPGVPVSEM 300
  301 IDPRFEEDYN VNYRHKRRHD ETYKHSELKN NKNVDGSDIM NWTGPGIFSD IIFEYMNNVL 360
  361 RYNSDILLIN PNLNKNDEEG SESATTPAKD VDNDTLSKST RKFYKKISES LQSSNSMPWE 420
  421 FFSFLKEPVI VDDVMVLPIT SFSPDVGQMG AQSSDDKMAF VKHMFSGSWK EDADKNAGHK 480
  481

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ANP1 GNT1 HOC1 KRE2 MNN10 MNN11 MNN9 OCH1 VAN1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen MRH1 OCH1 1 Unpublished Fields Lab Data
    View Screen HXK2 OCH1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data OCH1 and ANP1 Huh WK, et al. (2003)
    View Data OCH1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..58] deduced N/A No confident structure predictions are available.
    2 View Details [59..217] MSA 15.036997 View MSA. No confident structure predictions are available.
    3 View Details [218..480] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • UDP-glycosyltransferase activity
    		•  6.01354989568484 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  5.98555597307566 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  5.66606808201136 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  5.62955108548526 bayes_pls_golite062009
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  5.60505224219681 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  5.1732667004955 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  4.02812104984198 bayes_pls_golite062009
  • transferase activity
    		•  2.3313878748424 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.79751747857925 bayes_pls_golite062009
  • catalytic activity
    		•  1.73979371332125 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.47767908405723 bayes_pls_golite062009
  • N-acetyllactosamine synthase activity
    		•  0.925872529464618 bayes_pls_golite062009
  • lactose synthase activity
    		•  0.925872529464618 bayes_pls_golite062009
  • cytidylyltransferase activity
    		•  0.450701661234496 bayes_pls_golite062009
  • alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
    		•  0.386636074342689 bayes_pls_golite062009
  • binding
    		•  0.165472828059574 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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